Professor Michael A. GBADEGESIN

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Sarah O. NWOZO

Name: Michael A. GBADEGESIN

 Designation: Professor

Faculty: BASIC MEDICAL SCIENCES 
 Department:Biochemistry 
Phone Number: +234 7031975907

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Biography

Micheal A. Gbadegesin

Professor M. A. Gbadegesin received his BSc and MSc in Biochemistry, University of Ibadan and his PhD in Molecular Biology, University of Bath, UK. He was promoted to the grade of a Full Professor in Biochemistry, University of Ibadan, Ibadan, effectively 01 October 2017. His doctoral research training was in genomics, and he is currently actively engaged in aspects of toxicology of environmental contaminants and cancer genomics. His interests include molecular hepatotoxicity of environmental contaminants, and understanding of the genomics of chronic, non-communicable diseases such as cancer and diabetes.

Prof. Gbadegesin is the recipient/winner of many prestigious scholarships and fellowships such as the Commonwealth Scholarship, UK (2001-2004), Royal Society of Edinburgh Fellowship (2006), Rothamsted International African Fellowship (2008) etc. He took active part in the development of an integrated system-based, community-oriented, and competency-driven curriculum for medical students as a coordinator at pre-clinical level of training.

He is a competent teacher of biomedical courses across many academic departments at undergraduate and postgraduate levels. He is actively involved in capacity building and skills impartation through his teaching and research projects supervision. For instances, the following personnel passed through his tutelage: Oluwafemi Alaba (was his MSc student; now a Graduate Teaching Assistant at the University of Maine, US), Opeyemi Soremekun (was his MSc and PhD student; went to do PhD at the University of KwaZulu-Natal, South Africa, and now a Postdoc at MRC/UVRI & LSHTM, Uganda/UK), Olabode Omotoso (employ at African Genomics Company, Inqaba Biotec West Africa Ltd), John Teibo (a PhD student at University of Sao Paulo, Brazil) among others.

Research

1. 1994-95 University of Ibadan Senate Research Grant Award(1999)

2. Commonwealth Scholarship, Commonwealth Scholarship Commission, United Kingdom (2001-04)

3. Royal Society of Edinburgh Fellowship, at University of Dundee, UK  (2006)

4. Rothamsted International, African Fellowship (2008)

Publications

Selected Publications

YEAR

AUTHORS

TITLE

JOURNAL

VOL: Pages

2000

Gbadegesin MA, OA Odunola and AO Uwaifo

Protease inhibitor extract of fermented African locust beans (Parkia filicoidea) inhibits aflatoxin B1-induced rat liver glutamyl transferase activity. 

Biokemistri (Nigeria) 

10(2): 93-98.

2006

Raji Y, FO Awobajo, OT Kunle-Alabi, MA Gbadegesin and AF Bolarinwa

In vivo and in vitro Reproductive Toxicity Assessment of Ampicillin and Cloxacillin in Mammalian Models.

International Journal of Pharmacology (Pakistan) 

2(1): 9-14 

2006

Raji Y, MA Gbadegesin, OA Osonuga, RA Adisa, OS Akinsomisoye, FO Awobajo, OT Kunle-Alabi, PRC Esegbue-Peters, IO Osonuga and AF Lamidi

Reproductive, Haematologic and Biochemical Profiles of Male Rats Treated with Aqueous Extract of Spondias mombin Bark.

International Journal of Pharmacology (Pakistan)

2(1): 126-130.

2007

Raji YOT Kunle-Alabi, S.B. Olaleye, MA Gbadegesin, FO Awobajo, OA Osonuga, AO Odunkanmi, SA Salami and AF Bolarinwa

Impact of ?-tocopherol on Metronidazole- and Tetracycline-induced alterations in reproductive activities of male Albino Rats. 

Journal of Biological Sciences (Pakistan) 

7(1): 41-46.

2007

Gbadegesin MA, R Gomez-Vasquez, Reilly K and JR Beeching

Transcriptionally active Mutator-like transposable element in the genome of cassava (Manihot esculenta Crantz). 

Asian Journal of Plant Sciences (India) 

6(1): 129-136.  

2007

Odunola OA, MA Gbadegesin, SE Owumi and AO Uwaifo

Petroleum refining chemicals enhance aflatoxin B1-induced toxicities in Wistar rats. 

Journal of Med Science (Bangladesh)

7(4): 615-619. 

2008

Moyib OK, MA Gbadegesin, OO Aina and OA Odunola

Genetic variation within a collection of Nigerian accessions of African yam bean (Sphenostylis stenocarpa) revealed by RAPD primers. 

African Journal of Biotechnology (Kenya) 

7(12) 1839 – 1846.

2008

Odunola OA, E Uka,KA Akinwumi, MA Gbadegesin, OO Osifeso and MD Ibegbu

Exposure of Laboratory Mice to Domestic Cooking Gas: Implication for Toxicity.

International Journal of Environmental Research and Public Health (USA)

5 (3): 172-176.

2008

Gbadegesin, MA, MA Wills and JR Beeching

Diversity of LTR-retrotransposons and Enhancer/Suppressor Mutator-like transposons in cassava (Manihot esculenta Crantz).  

Molecular Genetic Genomics (Germany)

280: 305-17.

2009

Gbadegesin MA, OA Odunola, KA Akinwumi and OO Osifeso

Comparative hepatotoxicity and clastogenicity of sodium arsenite and three petroleum products in experimental Swiss Albino Mice: The modulatory effects of Aloe vera gel.

Food and Chemical Toxicol (England) 

47: 2454-2457.

2010

Gbadegesin MA and OA Odunola

Aqueous and ethanolic leaf extracts of Ocimum basilicum (sweet basil) protect against sodium arsenite-induced hepatotoxicity in Wistar rats. 

Nigerian Journal of Physiological Sciences (Nigeria)

25: 29-36.

2010

Gbadegesin MA and JR Beeching

Enhancer/SuppressorMutator (En/Spm)-like transposable elements of cassava (Manihot esculenta Crantz) are transcriptionally inactive.

Genetic and Molecular Research (Brazil) 

9(2): 639- 650. 

2011

Gbadegesin MA and JR Beeching

Highly Heterogeneous Ty3/Gypsy-like Retrotransposon Sequences in the Genome of Cassava (Manihot esculenta Crantz). 

African Journal of Biotechnology(Kenya) 

10 (20): 3951-3963

2010

Gbadegesin MA and JR Beeching

Isolation and partial characterisation of root specific promoters for stacking multiple traits into cassava (Manihot esculenta CRANTZ). 

Genetic and Molecular Research (Brazil) 

10(2): 1032-1041

ARTICLES SUBMITTED/ IN PRESS/ACCEPTED:

2011

Gbadegesin MA and JR Beeching

Analysis of heterogeneity of Copia-like retrotransposons in the genome of Cassava (Manihot esculenta Crantz)

Nigerian Journal of Physiological Sciences  

(Accepted)

2011

Gbadegesin MA, OA Odunola and SE Owumi

Chemoprotective activity and toxicity of Aloe vera in sodium arsenite treated Swiss Albino Mice. 

Journal of Science Research 

(Accepted)

PUBLISHED ABSTRACT:

2005

Gbadegesin MA, K Reilly and JR Beeching

Mutator-like transposable element of cassava (Manihot esculenta Crantz) is highly methylated. 

FEBS Journal 

272(s1): 47

2010

Owumi SE, OA Odunola, MA Gbadegesin, KL Nulah, A Mohammed, CO Oloye, AC Oloidi, MO Obadare and OO Oladeji

Chemoprotective properties of some African spices on sodium arsenite-induced toxicities in albino Wistar rats.

Cancer Prevention Research

3(12): B61

Supervision

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Grant

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