Dr. Sarah O. NWOZO

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 Nwozo

Name:  Sarah O. Nwozo

Designation: Reader
Faculty: Basic Medical Sciences
Department: Biochemistry
Phone Number:08023658268

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Brief Biography:

Dr. NWOZO Sarah Onyenibe is a Reader in Nutritional/ Industrial Biochemistry Unit of the Department of Biochemistry, FBMS, College of Medicine University of Ibadan, Ibadan. She holds a BSc (Hons) degree in Chemistry, MSc in Bioinorganic Chemistry and Ph.D. in Biophysical Chemistry. Her research focus is on medicinal foods (especially from fruits, vegetables and spices); Food Safety Evaluations; Free Radicals in Health and Diseases; Nutrition and non-Communicable Diseases and Chemoprotection. She has over sixty publications in peer review journals and has supervised many graduate students.

Research

Current Research and Capacity Building Projects including Grants

1. Title: Isolation, Characterization, Synthesis, and Enzyme Inhibitory assay of Celtiszenkeri(Prota)(Ulmaceae), Euphorbia graminea (Jacq) (Euphorbiaceae) and Macrosphyralongistyla (Rubiaceae).
Funder: Tetfund
Brief Summary: Celtiszenkeri (Prota)(Ulmaceae), Euphorbia graminea (Jacq) (Euphorbiaceae) and Macrosphyralongistyla (Rubiaceae) plants would be collected, authenticated and given voucher number. The leaves, stem, bark, and root bark would be air-dried in the laboratory and dried samples would be pulverized. Samples would be solvent extracted, fractionated, separated using chromatography and pure samples would be characterized using spectroscopic techniques. Bioassay guided separations would be done using enzyme inhibition assays.
Role: Co-Researcher
Collaborators: Prof. Patricia Onocha, Dr.Oloyede, and Dr.Okpala

 

2. Title: In vitro and in vivo study of the effectiveness of high-pressureacidified steaming on mycotoxin elimination from maize and peanut
Funder: Self-funded
Brief Summary: Food processing processes such as roasting, milling, sorting, frying, cold plasma, etc. have been studied for the removal of mycotoxins in foods. However, most of these studies reported incomplete or insufficient elimination of these mycotoxin-causing organisms. These studies have not sufficiently established the effects of food processing processes on the nutritional components and functional properties of the foods.This present study will explore the effectiveness of combining citric acid with high-pressure steaming on mycotoxin removal, as well as the impacts of this combination on the nutrients and functional properties of the grains under study. Steaming is moist-heat cooking method which involves boiling water until it vaporizes into steam.

Role: Supervisor
Collaborators: Nil

 

Publications

 

SELECTED PUBLICATIONS

 

Books

Sarah Nwozo Onyenibe, Josiah ifie, and Edith AjaiyeobaOriabure/Ram B Singh, Shaw Watsnabe and Adrian A. Isaza (2021) Use of plant foods from West Africa in the management of metabolic syndrome Elsevier CLICK HERE

Journal Articles

1. Ajaiyeoba, E.O., Onocha, P.A. , Nwozo, S.O. and Sama, W (2003) Antimicrobial and Cytotoxicity evaluation of Buchhoziacoriacea stem bark. Fitoterapia.

2. Nwozo, S.O., Osunmadewa, D.A. and Oyinloye, B.E. (2014) Anti-fatty liver effect of oils from Zingiber officinal and Curcuma longa on ethanol-induced fatty liver inrats Journal of Integrative Medicine.

3. Iwegbue, C.M.A., Nwozo, S.O., Ossai, E.K. and Nwajei, G.E. (2008) Heavy metalcomposition of some imported canned fruit drinks in Nigeria. American Journal of Food Technology.

4. Nwozo, S.O., Adaramoye, O.A. and Ajaiyeoba, E.O. (2004) Anti-diabetic andhypolipidemic studies of Telifairiaoccidentalis on alloxan induced diabeticrabbits. Nigerian Journal of Natural products and Medicine

5. Nwozo, S.O., Orojobi, F. and Adaramoye, O.A (2011) Hypolipidemic and antioxidantpotentials of Xylopiaaethiopica seed extract in hypercholesterolaemic rats Journal of medicinal Food.

6. Nwozo, S.O. and Oyinloye, B.E (2011) Hepatoprotective effect of aqueous extract ofAframomummelegueta on ethanol induced toxicity in rats ActaBiochimicaPolonica.

7. Nwozo, S.O., Lewis, Y.T. and Oyinlioye, B.E. (2017) The effects of Piper guineeseversus Sesamumindicum aqueous extracts on lipid metabolism and antioxidants inhypercholesterolemic rats Iran Journal of Medical Sciences.

8. Nwozo, S.O., Ozegbe, P.C. and Olusanya, O. (2017) Carbendazim alters kidneymorphology, kidney function test, tissue markers of oxidative stress and serum microelementsin rats fed protein-energy malnourished diet International Journal ofBiological and Chemical Sciences.

9. Nwozo, S.O., Okameme, P. E. and Oyinloye, B. E. (2012) Potential of Piper guineenseand Aframomumlongiscapum to reduce radiation induced hepatic damage in malewistar rats RadiatsBiolRadioecol.

10. Nwozo, S.O., Hammed, W.A. and Nwawuba, S.U. (2020) Ameliorative effects ofCajanuscajan on high-fat diet and streptozotocin-induced diabetes in male NewZealand rabbits World Heart Journal.

11. Wansi, J.D., Nwozo, S.O., Mbaze, L., Devkota, K.P., Moladje, S.M.D., Fomum, Z.T. and Sewald N (2009) Amides from the stem bark of Fagaramacrophylla Planta Medica.

12. Nwozo, S.O., Ajayi, A.I. and Obadare, M. (2010) Phytochemical screening andantimicrobial activity of 10 medicinal seeds from Nigeria Medicinal and Aromatic Plant Science and Biotechnology.

13. Iwegbue, C.M.A., Overah, C.L., Ebigwai, J.K., Nwozo, S.O., Nwajie, G.E. and Eguavoen O. (2011) Heavy metal contamination of some vegetables and spices in Nigeria International Journal of Biological and Chemical Sciences.

14. Nwozo, S.O., Ajayi, I.A. and Iorliam, B.E. (2013) Preliminary toxicologicalevaluation of some biochemical parameters and lipid profile in Thevetianerifolia seedoil supplemented diet in albino rats Leonardo Journal of Practices and Technology.

15. Nwozo, S.O. and Oyinloye, B.E. (2017) Piptadeniaafricana: enhances weight gain,oxidative stress, and hyperlipidemia in normal and hypercholesterolemic male Wistarrats Journal of Food and Pharmaceutical Sciences.

Supervision

SUPERVISION OF STUDENTS (Selected)

CURRENT STUDENTS

MastersLevel: Four students

Title of Dissertation

Student’s Name

Examining Body

Year of Entry

The protective role of high fibre from corn diet on high sucrose induced diabetic rat

Kazeem Abisola Ibironke

2019

Modulatory effect of wheat bran on lipid profile of rabbit exposed to high fat diet

Ishokare Lucia Oghenetejiri

2019

Essential oil from three local spices: Characterization and evaluation of biological effects on beef preservation

Ajakaiye Blessing

2019

Biochemical Association between Musa acuminate consumption and hyperkalemia in Wistar rat model

Angela M. Mosyoka

2020

 

Doctoral Level:One student

Title of Thesis

Student’s Name

Examining Body

Year of Entry

In vitro and in vivo study of the effectiveness of high-pressureacidified steaming on mycotoxin elimination from maize and peanut

 

Awuchi Chinaza

2020

 

PREVIOUS STUDENTS (Selected)

MastersLevel

 

Title of Dissertation

 

Student’s Name

 

Examining Body

Year Completion of study

Physiochemical properties, nutrients, anti-nutrients and bioactive antioxidants of juices produced from imported and local lesser known fruits.

OMOLABAKE Aladesuru Oluwaseun

Post-graduate School, University of Ibadan.

2017

Effects of mormodicacharantia and borhaaviadifusia in streptozotocin-induced type 2 diabetic male rats

MODEME Tochukwu Emmanuel

Post-graduate School, University of Ibadan.

2017

Radioprotective effects of n-hexane of telefariaoccidentalis and cucumeropsismanni seed oil on irradiated male rats

Ukeje Micheal O.

Post-graduate School, University of Ibadan.

2017

Radioprotective effect of cyperusesculentus and citrulluslanatus seed oils on gamma ray irradiated rats

Odusote Adeola Olugbenga

Post-graduate School ,University of Ibadan.

2017

Effect of methanolic extract of anacardiumoccidentale and azadirachtaindica  on streptozotocin-induced diabetic male rats

Afolabi Ayodeji Babatope

Post-graduate School, University of Ibadan.

2017

 

Grants

Current Grant Funding

1. Title: Isolation, Characterization, Synthesis, and Enzyme Inhibitory assay of Celtiszenkeri (Prota)(Ulmaceae), Euphorbia graminea (Jacq) (Euphorbiaceae) and Macrosphyralongistyla (Rubiaceae).
Funder: TETFUND
Brief Summary: Celtiszenkeri (Prota)(Ulmaceae), Euphorbia graminea (Jacq) (Euphorbiaceae) and Macrosphyralongistyla (Rubiaceae) plants would be collected, authenticated and given voucher number. The leaves, stem, bark, and root bark would be air-dried in the laboratory and dried samples would be pulverized. Samples would be solvent extracted, fractionated, separated using chromatography and pure samples would be characterized using spectroscopic techniques. Bioassay guided separations would be done using enzyme inhibition assays.
Role: Co-Researcher
Collaborators: Prof. Patricia Onocha, Dr.Oloyede, and Dr.Okpala

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Other Interests/Hobbies

Nwozo Interestsandhobbies

Cooking, gardening, and reading


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