Name: Samuel O. AJAYI Research Gate Profile Email: This email address is being protected from spambots. You need JavaScript enabled to view it. Alternate Email Address 1: This email address is being protected from spambots. You need JavaScript enabled to view it. Alternate Email Address 2: This email address is being protected from spambots. You need JavaScript enabled to view it. Biography: a. Current Research and Capacity Building Projects including Grants 2. Title: Kidney health in older persons. 3. Title: Genetic and urinary proteomic markers of kidney target organ damage in hypertensive black Africans. 4. Title: H3Africa Kidney Research Network. A multi-centre and multinational kidney research project aimed at elucidating the genetic and other factors causing kidney disease in Africa. 1. Kadiri, S. and Ajayi, S.O. (2000). Variability in the relationship between serum creatinine and creatinine clearance in hypertensives with normal renal function, African Journal of Medicine and Medical Sciences Vol. 29.0. pp 93-96 (Nigeria ) 2. Ajayi, S.O. (2009). Oxford Desk Reference of Nephrology and In Jonathan, B.,Kevin, H., Peter, T. (Ed). Glomerular Disease In the Tropics. New York: Oxford University Press. pp. ISBN: 9780199229567 (United Kingdom ) 3. Ajayi, S.O. and Harris, K.P.G. (2007). Hypertension and chronic kidney disease, Geriatric Medicine Vol. 37.4. pp 39-47 (United Kingdom ) 4. Ajayi, S.O. , Mamven, M.H. and Ojji, D.B. (2013). Risk assessment of adherence in hypertensives and diabetics in a sub-Saharan African outpatient clinic, African Journal of Health Sciences Vol. 25.0. pp 128-135 (Kenya ) (Contribution : 70%) 6. Ajayi, S.O. , Adebiyi, A. and Kadiri, S. (2018). Increased urinary sodium excretion is associated with systolic blood pressure in first degree relatives of hypertensive patients in Ibadan, Southwestern Nigeria, Pan african Medical Journal Vol. 31.168. pp 1-7 (Kenya ) 7. Raji, Y.R. , Ajayi, S.O. , Ademola, A.F. , Lawal, T.A. , Ayandipo, O.O. and Adigun, T.A. (2018). acute kidney injury among patients undergoing major surgery in a tertiary hospital in Nigeria , Clinical Kidney Journal Vol. 11.4. pp 443-449 (United Kingdom ) 8. Ajayi, S.O. , Adeoye, A.M. , Raji, Y.R. , Tayo, B. , Salako, B.L. , Ogunniyi, A. , Ojo, A. and Cooper, R. (2019). Self-reported sleep disorder and ambulatory blood pressure Phenotypes in patients with or without chronic kidney disease: findings from Ibadan CRECKID study, West african Journal of Medicine Vol. 36.1. pp 61-68 (Nigeria ) 9. Ekrikpo, U.E. , Okuku, C.N. , Ajayi, S.O. , Ayodele, O.E. , Bello, A.K. , Wonkam, A. , Dandara, C. , Kengne, A.P. and Okpechi, I. (2019). Urinary transforming growth Factor-Beta 1 (uTGF-β1) and prevalent CKD risk in HIVpositive patients in West Africa, Kidney International Reports Vol. 4.12. pp 1698-1704 (United States Of America ) 10. Ajayi, S.O. , Raji, Y.R. , Michael, O.S. , Adewole, D. , Akande, T. , Abiola, B. , Aminu, S. , Olugbenga-Bello A and Arije, A. (2021). Exposure to agrochemicals and markers of kidney damage among farmers in rural communities in Southwestern Nigeria, West African Journal of Medicine Vol. 38.1. pp 48-53 (Nigeria ) 11. Obideyi, T.O. , Raji, Y.R. , Ajayi, S.O. , Salako, B.L. , Arije, A. and Kadiri, S. (24th April, 2021). Correlation Between Albuminuria And Ankle Brachial Index Among Nigerians With Chronic Kidney Disease. African Journal Of Health Sciences (Kenya ) 12. Adebiyi, A.A. , Ajayi, S.O. and Ogunbiyi, A. (23rd June, 2021). Students’ Perception Of Computer Based Assessment System After A Pilot Experience in An African Medical School. Journal Of Medicine And Medical Sciences (Nigeria ) Fellowship Level 2. Alpha-thalassemia as a genetic modifier for Progression of CKD in Sickle cell Anaemia - Dr Olumuyiwa Oluwatoke, 2022 Fellowship 2. Ankle Brachial Pressure Index And Clinical Correlates In Chronic Kidney Disease At The University College Hospital, Ibadan. - Dr Temitope Bello, 2016Profile
Designation: Senior Lecturer
Faculty: CLINICAL SCIENCES
Department: Medicine
Phone Number: +234 803 471 3299
Research
1. Title: Risk factors for chronic kidney disease in HIV-infected patients in a treatment programme in Nigeria.
Funder: MEPINNIH/Fogarty
Summary: A number of kidney diseases are common in patients living with HIV. These include acute kidney injury, HIV-associated glomerulopathies, and chronic kidney diseases. It is therefore expected that the prevalence of HIV-related kidney diseases would be on the increase without anti-retrovirals. The objectives of the study are to determine the incidence and risk factors for kidney disease in patients living with HIV whether or not they are on treatment, and also determine the effectiveness of anti-retroviral treatment on reducing the incidence of HIV related kidney disease.
Role: Principal Investigator (PI)
Collaborator: Professors Solomon Kadir, Professor Georgina Odaibo
Funder: Self
Summary: This is a study of kidney diseases in older persons attending the geriatric clinic at the University College Hospital, Ibadan. The elderly have co-morbidities that impact their health and cause or aggravate kidney diseases. This study is being undertaken to define the risk factors with a view to outlining preventive measure for kidney health.
Role: PI
Collaborator: Dr Femi Olowookere
Funder: PAMAPS/Self
Summary: This study is elucidating renin angiotensin aldosterone system (RAAS) and kidney damage in patients with hypertension. The end-organ damage from hypertension is particularly more severe in African ancestry populations, and it would be interesting to know the relative contribution of RAAS. The overarching hypothesis of this study is that there is no association between urinary angiotensinogen level and kidney target organ damage (TOD) in black patients with essential hypertension in Ibadan, Nigeria.
Role: PI
Collaborator: Professor Ikechi Okpechi and Dr Udeme Ekrikpo
Funder: NIH
Summary: This study aims at establishing a kidney disease cohort of 4,000 participants and
4,000 controls (from a target population of 312 million in Ethiopia, Ghana, Kenya and Nigeria) for comprehensive phenotypic characterization and studies of interacting environmental factors. Perform genetic typing and analysis of known disease susceptible variants in the APOL1 and MYH9 genes and other renal candidate genes in a cohort of patients afflicted with sickle cell nephropathy, hypertensive nephrosclerosis, diabetic nephropathy, FSGS, HIV associated nephropathy and chronic glomerulonephritis. More than 5,000 study participants have already been recruited and two manuscripts have been published, and 16 being developed by the investigators.Publications
5. Ajayi, S.O. , Raji, Y. , Bello, T. , Jinadu, L. and Salako, B.L. (2015).Unaffordability of renal replacement therapy in Nigeria, Hong Kong Journal of Nephrology Vol. 10.18. pp 15-19 (China )Supervision
i. CURRENT STUDENTS
1. Intradialysis Hypertension And Its Risk Factors In University College Hospital Ibadan - Dr Osasogie Iyayi, 2022
PREVIOUS STUDENTS (Selected)
1. Clinical Correlates Of Haemodialysis Adequacy Among Patients On Maintenance Haemodialysis At University College Hospital (Uch), Ibadan - Dr Joshua Coker, 2020Social Media Handle
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Dr. Samuel O. AJAYI
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