Profile
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Name:Onoja M. AKPA |
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Designation: Professor |
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Faculty: PUBLIC HEALTH |
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Department: EPIDEMIOLOGY AND MEDICAL STATISTICS |
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Phone Number: +234 8032159579 |
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Email Address: This email address is being protected from spambots. You need JavaScript enabled to view it. Alternate Email Address: This email address is being protected from spambots. You need JavaScript enabled to view it. |
Biography:
Prof. Onoja Matthew Akpa hold a Ph. D. degree in Statistics from the University of Ilorin, Nigeria in 2009 but started a teaching career in 2005 as a lecturer with the Redeemer’s University. He is currently a Reader (i.e an Associate Professor) at the Department of Epidemiology and Medical Statistics, University of Ibadan, Nigeria. He has taught Biostatistics to both undergraduate and post graduate students from a wide range of academic background (including Clinical Medicine, Public Health, Veterinary medicine; Biology; Agriculture; and core Biostatistics). In addition, he has vast experience in handling large datasets arising from complex population-based surveys, observational studies and multi-site clinical studies in Africa and the USA. Such large datasets include the AIDS Clinical Trial Group (ACTG), USA; the Cardiovascular H3Africa Innovation Resource (CHAIR) of the H3Africa consortium; the National Health and Nutrition Examination Survey (NHANES) etc. He has held numerous international academic/research positions including visiting scholar, North-western University, Chicago, USA; Fogarty fellow, Centre for Biostatistics in AIDS Research (CBAR), Harvard University, Boston, USA; Postdoctoral fellow (Biostatistician), CHIAR group, H3Africa. He is currently the Acting Head of Department of Epidemiology and Medical Statistics, Faculty of Public Health, College of Medicine, University of Ibadan, Nigeria.
Area of Specialization
Dr. Akpa’s research activities focus mainly on statistical modeling and application of statistical methods to health-related outcomes. He developed and used both staged and dynamical models to investigate the transmission dynamics of HIV/AIDS in the General population of Nigeria. His works in this area were among the first efforts in modelling HIV transmission in Nigeria and he was the first to use and publish Statistical/Mathematical models for describing HIV trajectory and dynamics in Nigeria. During his Postdoctoral fellowship with the CHAIR group of the H3Africa, he harmonised data for >50,000 participants across 6 NIH funded studies, recruiting participants in 13 African countries; developed and led the largest and the first cross-study research in H3Africaa using the harmonized dataset. Dr. Akpa is a well collaborated Biostatistician within and outside of the College of medicine, University of Ibadan. He is an investigator on a number of NIH funded grants including the Stroke Investigative Research and Education Network (SIREN), the SIBS genomic study and the Eyes of Africa: The genetics of blindness.
Research
Completed Research
1)Title: Prevalence of HBV, HCV and HIV among Patients with and without Sickle Cell Disease in South West Nigeria
Funder: GILEAD SCIENCES
Brief Summary: The purpose of this study is to determine the frequency of infection with HBV, HCV and HIV among individuals with sickle cell disease (SS and SC patients), the risk factors associated with infection with these viruses, and the effect of these infections on hematological parameters. The study will also determine the circulating HBV, HCV and HIV types/subtypes/genotypes among individuals with SCD versus control group.
Role: Biostatistician
Collaborators: Adeyinka Falusi
2)Title: Epidemiology of Cardiovascular Diseases in sub-Saharan Africa
Funder: NIH
Brief Summary: The purpose of this study/job was to harmonize phenotypes and genomic data for >50,000 participants. It also involve integration of the genomics and phenomics data across six research studies making the CVD working group of H3Africa.
Role: Biostatistician
Collaborators: Mayowa Owolabi
3)Title: Stroke Investigative Research and Education Network (SIREN)
Funder: NIH
Brief Summary: This is a multidisciplinary collaborative research network of investigators in sub-Saharan Africa (SSA) and the United States collectively focused on exploring ways to promote a better understanding of the genetic and environmental risk factors for stroke among people of African ancestry. Funded under H3Africa consortium.
Role: Biostatistician
Collaborators: Mayowa Owolabi
4)Title: Tailored Hospital-¬based Risk Reduction to Impede Vascular Events after Stroke (THRIVES)
Funder: NIH
Brief Summary: The purpose of this study is to determine whether a culturally-sensitive multipronged post-discharge intervention can significantly reduce blood pressure, enhance achievement of guideline recommended targets for risk factor control, and lower recurrent vascular events in a low-income and middle-income (LMIC)..
Role: Biostatistician
Collaborators: Mayowa Owolabi
Publication
Journal Article
1)Akpa, O.M, Made F. and Owolabi M.O. (2020). Regional Patterns and Association Between Obesity and Hypertension in Africa: Evidence from the H3Africa CHAIR Study: Hypertension
2)Owolabi M.O., Gebregziabher M., Akpa O.M, Fakunle A. and Ovbiagele B. (2019). Randomized Trial of an Intervention to Improve Blood Pressure Control in Stroke Survivors: Circulation Cardiovascular Qualitative Outcomes.
3)Fred Stephen Sarfo, Bruce Ovbiagele, Akpa, O.M, Rufus Akinyemi, Mayowa Owolabi. (2020). Antecedent febrile illness and occurrence of stroke in West Africa: The SIREN study. Journal of the Neurological Sciences.
4)Agbola O.E, Akpa, O.M, Ojagbemi A. and Afolabi R.F. (2020). Multilevel Modelling of The Predictors of Post-Stroke Depression in South-West Nigeria: African Journal of Biomedical Research.
5)Olowoyo P, Okekunle AP, Ojagbemi A, Akpa, O.M. and Owolabi M. (2020). Green leafy vegetable intakes are inversely related to the incidence of stroke: European Journal of Preventive Cardiology.
6)Akpa, O.M, Okekunle A.P. and Owolabi M.O. (2021). Factors associated with hypertension among stroke-free indigenous Africans: Findings from the SIREN study: Journal Clinical Hypertension.
7)Akpa, O.M, Okekunle A.P, Asowata J.O. and Adedokun B. (2021). Passive smoking exposure and the risk of hypertension among non-smoking adults: the 2015-2016 NHANES data: Clinical Hypertension.
8)Cole J.W, Adigun T, Akinyemi R, Akpa, O.M, Bell S. and Grond-Ginsbach C. (2021). The copy number variation and stroke (CaNVAS) risk and outcome study: PLoS One.
9)Sarfo F.S, Akpa, O.M, Ovbiagele B. and Owolabi M.O. (2021). Influence of age on links between major modifiable risk factors and stroke occurrence in West Africa: Journal of the Neurological Sciences.
10)Olawoye O, Chuka-Okosa C, Akpa, O.M, Realini T. and Ashaye A. (2021). Eyes of Africa: The Genetics of Blindness: Study Design and Methodology: BMC Ophthalmology.
11)Akpa, O.M, Sarfo F.S, Owolabi M. and Ovbiagele B. (2021). A Novel Afrocentric Stroke Risk Assessment Score: Models from the Siren Study: Journal of Stroke Cerebrovascular Diseases.
12)Akpa, O.M, Okekunle A.P, Sarfo F.S. and Owolabi M.O. (2021). Sociodemographic and behavioural risk factors for obesity among community-dwelling older adults in Ghana and Nigeria: A secondary analysis of data from the SIREN study: Chronic Illness.
13)Oluwafemi Popoola, Bruce Ovbiagele, Akpa, O.M. and Mayowa Owolabi. (2022). African Rigorous Innovative Stroke Epidemiological Surveillance: Protocol for a Community-Based Mobile-Health Study: Neuroepidemiology.
14)Akinkunmi P.O, Osahon J.A, Boluwatife J.O, Olukunmi O.A. and Akpa, O.M. (2022). Community-based Investigation of the Risk Factors for Cardiovascular Diseases in Ibadan and suburbs (COMBAT-CVDs): Design and Methods: African Journal of Biomedical Science.
15)Akpa, O.M, Babalola O, Odetunde A and Fagbamigbe A. (2022). Correlates of transfusion transmissible infections among patients with sickle cell disease in Nigeria: case-control study: Journal of Immunoassay Immunochem.
16)Okekunle A, Asowata O, Akpa, O.M, Akinyemi R, Owolabi M. (2022). Dietary patterns associated with Stroke among West Africans: a case-control study: International Journal of Stroke.
17)Adebamowo C.A, Adeyemo A, Ashaye A, Akpa O.M, Chikowore T. and Adebamowo S.N. (2022). Polygenic risk scores for CARDINAL study: Nature Genetics.
Supervision
1) CURRENT STUDENTS
Master of Science (MSc.)
Doctoral level (Ph.D.)
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S/N |
Project Title |
Student’s Name |
Examining Body |
Year of Entry |
Degree |
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1 |
Martins, oluwatoyin olanike |
University of Ibadan |
2020 |
M.Sc. |
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Akinade, Mariam Oyindamola |
University of Ibadan |
2020 |
M.Sc. |
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3 |
Olayinka, Oluwafunmike D. |
University of Ibadan |
2020 |
M.Sc. |
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4 |
Bayesian Modelling of Trends and Patterns in Childhood Nutritional Status in Nigeria, 2008-2018. |
Olutola, Olaniyi Matthew |
University of Ibadan |
2019 |
Ph.D. |
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5 |
Voting-Dependent Artificial Neural Network (Vodann) Algorithms for Predicting Stroke Occurrence Among Indigenous Africans |
Asowata Osahon Jeffery |
University of Ibadan |
2021 |
Ph.D. |
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Development of Interrupted Mining Rules for Stroke Risk Factors and modeling using Deep Learning Algorithms |
Fowobaje, Kayode Felix |
University of Ibadan |
2021 |
Ph.D. |
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7 |
Modelling the estimates and risk factors for poor maternal, neonatal and child health (MNCH) outcomes in Africa using Bayesian Cox Regression |
Agbola, Emmanuel Oluseyi |
University of Ibadan |
2021 |
Ph.D. |
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Bayesian hierarchical modeling: an application to Coronary Heart Disease |
Akingbade, Akeem Adekunle |
University of Ibadan |
2021 |
Ph.D. |
2) PREVIOUS STUDENTS(SELECTED)
Master of Science (MSc.)
Doctoral level (Ph.D.)
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S/N |
Project Title |
Student’s Name |
Examining Body |
Year of Completion of Study |
Degree |
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1 |
Modeling risk factors for obesity and hypertension among HIV seropositive patients using generalised estimating equation |
Odubela Olayemi Rafiah |
University of Ibadan |
2021 |
M.Sc. |
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Modelling Risk Factors for Lipid Profile Among Out-Patient of University College Hospital Ibadan Using Structural Equation Models |
Okesipe Bukola Kikelomo |
University of Ibadan |
2021 |
M.Sc. |
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2 |
Assessing Factors Associated with Psychosocial Functioning of Adolescents using Generalized Additive Models |
Isamot Omodolapo Waliyat |
University of Ibadan |
2021 |
M.Sc. |
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3 |
Modeling risk factors for diabetes among out-patients of University College Hospital Ibadan, using structural equation models. |
Akintunde Aishat Taiwo |
University of Ibadan |
2021 |
M.Sc. |
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4 |
Epidemiology and Medical Statistics, College of Medicine, University of Ibadan |
Benson Eweghoro |
University of Ibadan |
2019 |
Ph.D. |
Grants
CURRENT GRANT FUNDING
1) Title: Systematic Investigation of Blacks with Stroke using Genomics (SIBS Genomics)
Funder: NIH
Brief Summary: Systematic Investigation of Blacks with Stroke using Genomics (SIBS Genomics) is to discover, validate and functionally characterize novel genetic variants associated with ischemic stroke in people of African ancestry.
Role: Biostatistician
Collaborators: Mayowa O. Owolabi
2) Title: Eyes of Africa: the genetics of blindness
Funder: NIH
Brief Summary: The purpose of this study is to identify the optimal approach for early treatment of glaucoma and conduct Targeted Glaucoma Screening in Sub Saharan Africa (TGS-SSA): An approach to identify glaucoma early and increase awareness of glaucoma in Sub-Saharan Africa. Successful completion will identify pre-symptomatic glaucoma for treatment, educate families about the disease, and identify highly penetrant mutations that give rise to early onset glaucoma. Funded under H3Africa consortium.
Role: Statistical geneticist
Collaborators: Mayowa O. Owolabi
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