Basic Information
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Name: Dr. Amos O. ABOLAJI |
Faculty: BASIC MEDICAL SCIENCES |
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Email: This email address is being protected from spambots. You need JavaScript enabled to view it. |
Department:Biochemistry | |
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Designation: Senior Lecturer |
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Brief Biography: |
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Resume
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NAME: ABOLAJI, Olalekan Amos |
POSITION: AREA OF SPECIALISATION: |
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INSTITUTION AND LOCATION |
DEGREE |
YEAR(s) |
FIELD OF STUDY |
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Obafemi Awolowo University, Ile-Ife, Nigeria University of Lagos, Lagos, Nigeria University of Calabar, Calabar, Nigeria |
B.Sc. M.Sc. Ph.D. |
1998 2003 2010 |
Bachelor of Science Master of Science Doctor of Philosophy |
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SCHOLARSHIPS, FELLOWSHIPS AND PRIZES |
DETAILS |
YEARS |
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2018 Africa Oxford Initiative Fellowship (Academic Visitor) |
Department of Biochemistry, University of Oxford, UK. |
August 2018 - September 2018 |
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SOT/AstraZeneca/SOT Endowment Fund Travel Award |
To attend and make presentation at the 2015 Society of Toxicology Annual Meeting, in San Diego, CA |
March 22–26, 2015 |
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2012/2013 CNPq-TWAS Postdoctoral Fellowship Award |
Award of Postdoctoral Fellowship by the Brazilian National Council for Scientific and Technological Development (CNPq) and TWAS, the Academy of Sciences for the Developing World. To investigate ‘Molecular and Biochemical Toxicity Studies on 4-Vinylcyclohexene and its metabolites in Drosophila melanogaster model’ at the Federal University of Santa Maria, Centre for Natural Sciences, Department of Biochemical Molecular Biology, Biochemical Toxicology Unit, Brazil |
April 2013-March 2014 |
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2008/2009 Joint NAM S&T-ICCBS PhD Sandwich Fellowship |
Non-Aligned and other Developing Countries Science and Technology Centre, India in conjunction with the International Centre for Chemical and Biological Sciences (ICCBS) University of Karachi, Pakistan.To carry out part of my Ph.D. bench work at the Dr Panjwani Centre for Molecular Medicine and Drug Research, University of Karachi, Pakistan |
2008-2009 |
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WHO/TDR Travel Fellowship Award |
Fifth MIM Pan-African Malaria Conference Nairobi, Kenya |
2-6 November 2009 |
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MEMBERSHIP OF LEARNED SOCIETIES |
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· European Teratology Society · American Society of Biochemistry and Molecular Biology · Society of Toxicology, USA · Medicinal Plants Research, Germany |
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EMPLOYMENT HISTORY |
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Adjunct Lecturer: Department of Biochemistry, Adeleke University, Ede, Osun State, Nigeria |
2015 |
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Adjunct Lecturer: Landmark University, OmuAran, Kwara State, Nigeria |
2016 |
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Visiting Lecturer: University of Oxford, U.K. |
February, 2019 |
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PROFESSIONAL |
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(a)Selected Areas of Teaching · Chemistry and Metabolism of Carbohydrates · Chemistry and Metabolism of Proteins · Comparative Biochemistry · Advanced Lipid Biochemistry · Biochemistry and Immunology of Parasitic Diseases · Biochemistry of Nucleic Acids · Biochemical Toxicology (b)Administrative Experience University of Ibadan · Postgraduate Departmental Coordinator 2017 · Assistant B.Sc. Coordinator 2011-2015 · Member, Departmental Academic Board 2011-Date · Coordinator, MBBS/BDS programme 2015 Covenant University · Member, Convocation Subcommittee in charge of Media. 2010 · Chairman, Media Subcommittee of International Biotechnology Symposium (IBS) 2009-2010 · 400 Level students’ Adviser 2009-2010 · 100 Level students’ Adviser 2007-2008 · Assistant Departmental Examination Officer 2007-2008 |
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Researches
RESEARCH
Completed Research
| YEAR(S) |
RESEARCH NAME |
| 2010 | Standardisation of Nigerian Grown Artemisia annua using Reversed Phase High Performance Liquid Chromatography |
| 2010 | Reproductive and Biochemical assessment studies on Local Artemisia annua in Wistar rats |
| 2010 | Contraceptive potential of Artemisia annua in female rats |
| 2011-2012 | Reproductive Toxicity Assessment Studies on artemisinin, artemether-lumefantrine and artesunate-amodiaquine in rats |
| 2012 | Reproductive Toxicity Study on 2,5-Hexanedione in rats |
| 2013 | Molecular and Biochemical Toxicity Studies on ovotoxicant 4 -Vinylcyclohexene using Drosophila melanogaster as a model |
| Toxicological Studies on ovotoxicants 4-Vinylcyclohexene monoepoxide and 4-Vinylcyclohexene diepoxide in Drosophila melanogaster | |
| Possible chemopreventive effect of diphenyl diselenide on mercuric chloride-induced reproductive toxicity in female Wistar rats | |
| Reproductive toxicity study on 4-Vinylcyclohexene diepoxide in male and female Wistar rats | |
| Reproductive toxicity studies on trichloroethyelene in female Wistar rats | |
| Chemopreventive potential of hesperidin against trichloroethyelene-induced toxicity in Drosophila melanogaster |
Ongoing Research
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RESEARCH NAME |
| Rescue potential of curcumin on Cu2+-induced neurotoxicity in healthy (Wild Type) and Alzheimer`s disease model of Drosophila melanogaster |
| Rescue role of curcumin in aluminium chloride-induced neurotoxicity in healthy and Alzheimer`s disease D. melanogaster |
Dissertation and Thesis
| YEAR(S) | RESEARCH NAME |
| 2010 | Standardisation, Biochemical and Reproductive Toxicity studies on Local Artemisia annua in Wistar rats |
Publications
PUBLICATIONS
| Years | Authors | Title | Journals | Vol: pages |
| 2018 | Farombi E.O., Abolaji A.O.,Adetuyi B., Awosanya O., Fabusoro M. | Neuroprotective role of 6-Gingerol-rich fraction of Zingiber officinale (Ginger) against acrylonitrile-induced neurotoxicity in male Wistar rats | J Basic Clin Physiol Pharmacol | doi: 10.1515/jbcpp-2018-0114 |
| 2018 | Nkpaa K.W., Awogbindin I.O., Amadi B.A., Abolaji A.O., Adedara I.A., Wegwu M.O., Farombi E.O. | Ethanol exacerbates manganese-induced neurobehavioral Deficits, striatal oxidative stress, and apoptosis via regulation of p53, Caspase-3, and Bax/Bcl-2 ratio-dependent pathway | Biol Trace Elem Res | doi: 10.1007/s12011-018-1587-4 |
| 2018 | Abolaji A.O., Adedara A.O., Adie M.A., Vicente-Crespo M., Farombi E.O. | Resveratrol prolongs lifespan and improves 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced oxidative damage and behavioural deficits in Drosophila melanogaster | Biochemical and Biophysical Research Communications | 503: 2, 1042-1048 |
| 2018 | Farombi EO, Abolaji AO,Farombi TH, Oropo AS, Owoje OA, Awunah MT. | Garcinia kola seed biflavonoid fraction (Kolaviron), increases longevity and attenuates rotenone-induced toxicity in Drosophila melanogaster | Pestic Biochem Physiol | 145: 39 ? 45 |
| 2018 | Kamdem JP, Roos DH, Sanmi AA, Calabró L, Abolaji AO, de Oliveira CS, Barros LM, Duarte AE, Barbosa NV, Souza DO, Rocha JBT | Productivity of CNPq Researchers from Different Fields in Biomedical Sciences: The Need for Objective Bibliometric Parameters-A Report from Brazil | Sci Eng Ethics | doi: 10.1007/s11948-018-0025-5 |
| 2018 | Akinyemi AJ, Oboh G, Ogunsuyi O, Abolaji AO,Udofia A. | Curcumin-supplemented diets improve antioxidant enzymes and alter acetylcholinesterase genes expression level in Drosophila melanogaster model. | Metab Brain Dis | 33: 2, 369 ? 375 |
| 2018 | Adebayo O.A., Adesanoye O.A., Abolaji, A.O., Kehinde, A.O., Adaramoye, O.A. | Administration of first line anti-tuberculosis drugs induces ovarian and uterine oxidative stress and disruption of endocrine balance in rats | J Basic Clin Physiol Pharmacol | 29: 2, 131?140 |
| 2017 | Abolaji AO, Babalola OV, Adegoke AK, Farombi EO. | Hesperidin, a citrus bioflavonoid, alleviates trichloroethylene-induced oxidative stress in Drosophila melanogaster | Environ Toxicol Pharmacol. | 55:202?207 |
| 2017 | Abolaji AO, Ojo M, Afolabi TT, Arowoogun MD, Nwawolor D, Farombi EO. | Protective properties of 6-gingerol-rich fraction from Zingiber officinale (Ginger) on chlorpyrifos-induced oxidative damage and inflammation in the brain, ovary and uterus of rats | Chem Biol Interact | 270: 15?23 |
| 2017 | Abolaji AO, Olaiya CO, Oluwadahunsi OJ, Farombi EO. | Dietary consumption of monosodium L-glutamate induces adaptive response and reduction in the life span of Drosophila melanogaster | Cell Biochem Funct | 35: 3, 64 - 170 |
| 2017 | Adedara I.A., Abolaji A.O.,Idris U.F., Olabiyi B.F., Onibiyo E.M., Ojuade T.D., Farombi E.O. | Neuroprotective influence of taurine on sodium fluoride-induced biochemical and behavioral deficits in rats | Chemico-Biological Interactions | 261: 1 - 10 |
| 2017 | Adedara I.A., Abolaji A.O.,Awogbindin I.O., Farombi E.O. | Suppression of the brain-pituitary-testicular axis function following acute arsenic and manganese co-exposure and withdrawal in rats | Journal of Trace Elements in Medicine and Biology | 39: 21 - 29 |
| 2017 | Abolaji A.O., Awogbindin I.O., Adedara I.A., Farombi E.O. | Insecticide chlorpyrifos and fungicide carbendazim, common food contaminants mixture, induces hepatic, renal, and splenic oxidative damage in female rats | Human and Experimental Toxicology | 36: 5, 483 - 493 |
| 2017 | Adedara I.A., Abolaji A.O.,Ladipo E.O., Fatunmibi O.J., Abajingin A.O., Farombi E.O. | 4-Vinylcyclohexene diepoxide disrupts sperm characteristics, endocrine balance and redox status in the testes and epididymis of rats | Redox Report | 22: 6, 388 - 398 |
| 2016 | Abolaji A.O., Adedara I.A., Abajingin A.O., Fatunmibi O.J., Ladipo E.O., Farombi E.O. | Evidence of oxidative damage and reproductive dysfunction accompanying 4-vinylcyclohexene diepoxide exposure in female Wistar rats | Reproductive Toxicology | 66: 10 - 19 |
| 2016 | Abolaji A.O., Toloyai P.E., Odeley T.D., Akinduro S., Rocha J.B., Farombi E.O. | Hepatic and renal toxicological evaluations of an industrial ovotoxic chemical, 4-vinylcyclohexene diepoxide, in both sexes of Wistar rats | Environmental Toxicology and Pharmacology | 45: 28 - 40 |
| 2016 | Abolaji A.O., Adesanoye O.A., Awogbindin I., Farombi E.O. | Endocrine disruption and oxidative stress implications of artemether-lumefantrine combination therapy in the ovary and uterus of rats | Human Experimental Toxicology | 35: 11, 1173 - 1182 |
| 2016 | Kamdem J.P., Abolaji A.O.,Elekofehinti O.O., Omotuyi I.O., Ibrahim M., Waseem Hassan, Barbosa N.V., Souza D.O., Rocha J.B | Therapeutic potential of plant extracts and phytochemicals against brain ischemia-reperfusion injury: A Review | The Natural Products Journal | 6: 4, 250 - 284 |
| 2016 | Kamdem J.P., Abolaji A.O.,Roos D.H., Calabró L., Barbosa N.V., Souza D.O., Rocha J.B | Scientific Performance of Brazilian Researchers in Pharmacology with grants from CNPq: A comparative study within the Brazilian categories | Anais Da Academia Brasileira De Ciencias | 88: 3, 1735 - 1742 |
| 2016 | Adedara I.A., Abolaji A.O.,Odion B.E., Omoloja A.A., Okwudi I.J., Farombi E.O. | Redox status of the testes and sperm of rats following exposure to 2,5-hexanedione. | Redox Report | 21:6, 239 - 247 |
| 2016 | Adedara I.A., Abolaji A.O.,Rocha J.B.T., Farombi E.O | Diphenyl diselenide protects against mortality, locomotor deficits and oxidative stress in Drosophila melanogaster model of manganese-induced neurotoxicity | Neurochemical Research | 41: 6, 1430 - 1438 |
| 2015 | Abolaji A.O., Kamdem J.P., Lugokenski T.H., Farombi E.O., Souza D.O., Loreto E.L., Rocha J.B | Ovotoxicants 4-vinylcyclohexene 1,2-monoepoxide and 4-vinylcyclohexene diepoxide disrupt redox status and modify different electrophile sensitive target enzymes and genes in Drosophila melanogaster | Redox Biology U.S.A. | 5: 328 - 339 |
| 2015 | Waczuk E.P., Kamdem J.P., Abolaji A.O., Meinerz D.F, Bueno D.C., Nascimento T.K., Dorow T.S., Boligon A.A., Athayde M.L., Rocha J.B., Avila D.S | Euphorbia tirucalli aqueous extract induces cytotoxicity, genotoxicity and changes in antioxidant gene expression in human leukocytes | Toxicology Research U.K. | 4: 739 - 748 |
| 2014 | Abolaji,A.O., Kamdem, J.P., Lugokenski, T.H., Nascimento, T.K., Waczuk, E.P., Farombi, E.O., Loreto, E.L., Rocha J.B.T. | Involvement of oxidative stress in 4-vinylcyclohexene-induced toxicity in Drosophila melanogaster. Free Radical | Biology and Medicine, U.S.A. | 71: 99 - 108 |
| 2014 | Abolaji A.O., Eteng M.U., Ebong P.E., Dar A., Farombi E.O., Choudhary M.I. | Artemisia annua as a possible contraceptive agent: a clue from mammalian rat model | Natural Product Research UK | 24: 2342 - 2346 |
| 2014 | Farombi, E.O., Adedara, I.A., Abolaji, A.O., Anamelechi, J.P., Sangodele, J.O. | Sperm characteristics, antioxidant status and hormonal profile in rats treated with artemisinin | Andrologia. Germany | 46: 8, 893 - 901 |
| 2014 | Filho, V.M., Waczuk, P.W., Kamdem, J.P., Abolaji, A.O.,Lacerda, S.R., Costa, J.G., Menezes, I.R., Boligon, A.A., Athayde, M.L., Rocha, J.B., Thais, P. | Phytochemical constituents, antioxidant activity, cytotoxicity and osmotic fragility effects of Caju (Anacardium microcarpum) | Industrial Crops and Products. Netherlands | 55: 280 - 288 |
| 2014 | Farombi, E.O., Abolaji, A.O., Adedara, I.A., Soladogun, A., Salau, V., Oguaka, M. | Oxidative stress and changes in antioxidative defence system in erythrocytes of female rats exposed to 2, 5-Hexanedione. | Archives of Basic and Applied Medicine. Nigeria | 2: 29 - 33 |
| 2014 | Farombi, E.O., Abolaji, A.O., Adedara, I.A., Maduako, I., Omodanisi, I. | Artemisinin induces hormonal imbalance and oxidative damage in the erythrocytes and uterus but not in the ovary of rats. | Human and Experimental Toxicology. UK | 34: 1, 83 - 92 |
| 2014 | Adedara I.A., Abolaji A.O., Odion B., Okwudi I., Omoloja A., Farombi E.O. | Impairment of hepatic and renal functions by 2,5-hexanedione is accompanied by oxidative stress in rats | Journal of Toxicology | doi: 10.1155/2014/239240 |
| 2014 | Ogunbolude Y., Ibrahim M., Elekofehinti O.O., Adeniran A., Abolaji A.O., Rocha J.B.T., Kamdem J.P. | Effects of Tapinanthus globiferus and Zanthoxylum zanthoxyloides extracts on human leukocytes in vitro | Journal of Intercultural Ethnopharmacology. Turkey | 3: 4, 167 - 172 |
| 2013 | Abolaji, A.O., Eteng, M.U., Omonua, O., Adenrele, Y. | Influence of co-administration of artemether and lumefantrine on selected plasma biochemical and erythrocyte oxidative stress indices in female Wistar rats. | Human and Experimental Toxicology. UK | 32: 2, 206 - 215 |
| 2013 | Abolaji, A.O, Eteng, U.M., Ebong, P.E., Brisibe, E.A., Dar, A., Kabir N., Choudhary M.I. | A safety assessment of the antimalarial herb Artemisia annua during pregnancy in Wistar rats | Phytotherapy Research | 27: 5, 647 - 654 |
| 2013 | Eteng, M.U., Abolaji, A.O., Ebong, P.E., Brisibe, E.A., Dar A., Kabir N., Choudhary M.I. | Biochemical and haematological evaluation of repeated doseexposure of male Wistar rats to an ethanolic extract of Artemisiaannua | Phytotherapy Research. UK | 27: 4, 602 - 609 |
| 2013 | Abolaji, A.O., Kamdem, J.P., Farombi, E.O., Rocha, J.B.T. | Drosophila melanogaster as a promising model organism in toxicological studies. A mini review | Archives of Basic and Applied Medicine. Nigeria | 1: 33 - 38 |
| 2013 | Abolaji, A.O., Osedeme, F., Olusemire, O. | Artesunate-amodiaquine combination therapy in the absence of malarial parasite infection induces oxidative damage in female rats. | Cell Biochemistry and Function. UK | 32: 303 - 308 |
| 2012 | Olasehinde, G.I., Yah, C.S., Singh, R, Ojurongbe, O. O., Ajayi, A.A., Valecha, N, Abolaji, A.O., Adebiyi, M.O., Adeyeba, O.A. | Genetic diversity of Plasmodium falciparum field Isolates from South Western Nigeria | African Health Sciences. Uganda | 12: 3, 355 - 361 |
| 2011 | Adebayo, A.H., Abolaji, A.O., Kela R., Oluremi, S.O., Owolabi, O.O., Ogungbe, O.A. | Hepatoprotective activity of Chrysophyllum albidum against carbon tetrachloride-induced hepatic damage in rats. | Canadian Journal of Pure and Applied Sciences. Canada | 5: 3, 1597 - 1602 |
| 2011 | Adebayo, A.H, Abolaji, A.O., Kela, S. Ayepola, O.O., Olorunfemi, T., Taiwo, O.S. | Antioxidant activities of the leaves of Chrysophyllum albidum G. | Pakistan Journal of Pharmaceutical Sciences. Pakistan | 24: 4, 545 - 551 |
| 2010 | Eteng, M.U., Ekwe, A.O., Abolaji, A.O., Eyong, E.U., Ibekwe, H.A., Osuchukwu, N.C. | Biochemical and haematological changes in pregnant malaria patients and pregnant non-malaria women | Scientific Research and Essays. Nigeria | 5: 9, 1009 - 1013 |
| 2010 | Abolaji, A.O., Eteng, M.U., Ebong, P.E., Brisibi, A., Shakil, A., Erum, S., Choudhary, M.I | Standardisation of Artemisia annua using Reversed Phase High Performance Liquid Chromatography (RP-HPLC) | Pharmacognosy Journal. India | 2: 7, 143 - 147 |
| 2010 | Adebayo, A.H., Abolaji, A.O., Opata, T.K., Adegbenro, I.K. | Effects of ethanolic leaves extract of Chrysophyllum albidum G. on biochemical and haematological parameters of albino Wistar rats | African Journal of Biotechnology. Kenya | 9: 14, 2145 -- 2150 |
| 2009 | Eteng, M.U., Ibekwe, H.A., Abolaji, A.O., Okoi, A. I., Onwuka, F. C., Osuchukwu, N.C | Effect of Rauwolfia vomitoria Afzel (Apocynaceae) extract on serum amino transferase and alkaline phosphatase activities and selected indices of liver and kidney functions | African Journal of Biotechnology. Kenya | 8: 18, 4604 - 4607 |
| 2008 | Eteng, M.U., Ukpanukpong, R.U., Abolaji, A.O, Eyong, E.U., Egbung, E. | Biochemical and histological alteration and effect of perfloxacin on Wistar rats reproductive function | Australian Journal of Basic and Applied Sciences. Jordan | 2: 3, 475 - 480 |
| 2008 | Eteng, M.U., Onwuka, F.C., Umoh, I.B., Abolaji, A.O. | Trans-generational effects of cadmium toxicity on gonadal steroid levels and reproductive outcome of Wistar rats | Journal of Applied Sciences Research. India | 4: 7, 925 - 928 |
| 2008 | Eteng, M.U., Bassey, B.J., Atangwho, I.J., Egbung, G.E., Eyong, E.U., Ebong, P.E., Abolaji, A.O. | Biochemical indices of macrovascular complication in diabetic rat model: Compared effects of Vernonia amygdalina, Cathanrantus roseus and Chlorpropamide | Asian Journal of Biochemistry. India | 3: 4, 228 - 234 |
| 2007 | Abolaji, A.O., Adebayo, A.H., Odesanmi, O.S. | Effects of ethanolic fruit extract of Parinari polyandra (Rosaceae) on serum lipid profile and some electrolytes in pregnant rabbits | Research Journal of Medicinal Plant. Kenya | 1: 4, 121 - 127 |
| 2007 | Abolaji, A.O., Adebayo, A.H., Odesanmi, O.S. | Nutritional qualities of three medicinal plant parts (Xylopia aethiopica, Blighia sapida and Parinari polyandra) commonly used by pregnant women in the western part of Nigeria | Pakistan Journal of Nutrition | 6: 6, 665 - 668 |
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