Name: Temidayo O. OGUNDIRAN Email: This email address is being protected from spambots. You need JavaScript enabled to view it. Alternate Email Address 1: This email address is being protected from spambots. You need JavaScript enabled to view it. Alternate Email Address 2: This email address is being protected from spambots. You need JavaScript enabled to view it. Biography: Temidayo Ousade Ogundiran Temidayo Olusade Ogundiran attended the University of Ibadan and graduated as one of the two best students in the Department of Medicine in 1988. He was also a co-winner of the University College Hospital (UCH) Ibadan Best Houseman award for the year 1988/89. Dr. Ogundiran trained in General Surgery at the UCH Ibadan and became a fellow of the West African College of Surgeons (WACS) in 1996, the Royal College of Surgeons of Edinburgh in 1999, and the American College of Surgeons in 2011. He received further academic and professional training in the UK, Hong Kong, Kenya, and the USA. These include the Final FRCS Course at Caithness General Hospital, Wick, Scotland (1999); the American Association for Cancer Research (AACR) training in ‘Molecular Biology in Clinical Oncology’ at Given Institute, University of Colorado, Aspen, USA (2006); Oncology preceptorship at the Massachusetts General Hospital, Dana-Farber Cancer Institute, and Brigham and Women’s Hospital, all in Boston, USA (2006), Cancer molecular biology training at the Cancer Signalling Unit, Department of Clinical Oncology, Chinese University of Hong Kong, Hong Kong (2007); and Breast cancer clinical observer program, Memorial Sloan Kettering Cancer Centre, New York City, USA (2013). In 2003/2004, he utilized a Fogarty International Fellowship to obtain a Master of Health Science degree in Bioethics from the Joint Centre for Bioethics, Institute of Medical Science, University of Toronto, Canada. Dr. Ogundiran’s interests are in Surgery, Oncology and Bioethics. His main research focus is on genetics of breast cancer in Blacks. With the University of Chicago USA, his team explored the roles that genetics and environmental factors play in breast-cancer risk in Nigerian women and in women of African ancestry. They further correlated their work with findings in women of European and Asian extractions and developed a breast cancer risk-prediction model for Sub-Sahara Africa that can identify high-risk individuals for targeted screening and follow-up. Dr. Ogundiran is a foundation member of the West African Bioethics (WAB) Training Program, an NIH-funded initiative, now called Center for Bioethics and Research, Nigeria. He is the Academic Director of the Center to date. The WAB established a postgraduate program in Bioethics in 2007 at the University of Ibadan, which has grown into a full Department of Bioethics and Medical Humanities with Dr. Ogundiran serving as its first Head of Department. He has contributed to more than 120 book chapters and journal articles, has a Google Scholar citation of 4754, h-index of 35 and i10-index of 64 as at December 2023. He has received many scholarships and awards, supervised over 30 postgraduate and fellowship research projects, and has contributed to the training of more than 20 General Surgeons. He was promoted full Professor of Surgery in 2014. Dr. Ogundiran has served on many academic, professional and editorial committees. He was a co-winner of the 2018 Nigerian Academy of Science Gold Medal Prize in Life Sciences, and a 2019 winner of the WACS’s Victor Anomah Ngu lectureship. He is the current Dean of the Faculty of Clinical Sciences. On June 8, 2023, he delivered the 526th University of Ibadan Inaugural Lecture. Current Research and Capacity Building Projects including Grants 1. Environmental and Genetic Risk Factors for Soft Tissue Sarcomas in Nigeria– A study of the risk factors for soft tissue sarcoma. 2. Bridging Gaps in the ELSI of Data Science Health Research in Nigeria (BridgELSI). 3. Eastern Nigeria Research Ethics Training (ENRICH) Program, University of Nigeria Teaching Hospital, Enugu. MSc and MPH Bioethics programs at the University of Nigeria, Enugu Campus. 4. Scaling Up Research Ethics and Research Integrity (SURER) Project. MSc Bioethics training in Responsible Conduct of Research. Completed Research 1. Phase 1 of Genetics of breast cancer in black women, a multidimensional international collaborative study of epidemiological risk factors for breast cancer in Nigeria 2. Phase II of Genetics of breast cancer in black women- A collaborative study with the University of Chicago on genetic and epidemiological risk factors for breast cancer in black women in Nigeria and the diaspora. The focus was on genome wide association studies to look for low penetrance genes in the aetiology of breast cancer in blacks 3. A phase 11 study to evaluate the efficacy, safety and genomic markers of response of capecitabine as Neoadjuvant therapy in women with newly diagnosed locally advanced breast cancer (Xeloda trial) 4. Surgeon-patient communication in Nigeria 5. Male breast cancer in Ibadan 6. Informed consent in genetic research 7. Medical ethics education in medical schools in Nigeria 8. Tamoxifen ocular toxicity in breast cancer patients 9. Evaluation of the Social, Economic and Psychological Impact and Quality of life (SEPIQ) of breast cancer on patients at the University College hospital Ibadan 10. International Breast Cancer Study Group (IBCSG) Trial 22-00: Maintenance chemotherapy in hormone non-responsive breast cancer: low dose cytotoxics as "Anti-angiogenesis treatment" following adjuvant induction chemotherapy for patients with ER-negative and PgR negative breast cancer SELECTED PUBLICATIONS 1. Adebamowo CA, Callier S, Akintola S, Maduka O, Jegede A, Arima C, Ogundiran T, Adebamowo SN; BridgELSI Project as part of the DS-I Africa Consortium. The promise of data science for health research in Africa. Nat Commun. 2023 Sep 29;14(1):6084. doi: 10.1038/s41467-023-41809-2. PMID: 37770478 2. Ayandipo OO, Ogundiran TO. Acute abdomen, intestinal obstruction and gastrointestinal haemorrhage. In “Basic Principles and Practice of Surgery”. Publisher: TETFund. (Editors: Frank C Akpuaka, Martin AC Aghaji, Emmanuel A Ameh). In Print 3. Bryan MS, Ogundiran T, Ojengbede O, Zheng W, Blot W, Domcheck S, Hennis A, Nemesure B, Ambs S, Olopade OI, Huo D. Associations between age of menarche and genetic variation in women of African descent: genome-wide association study and polygenic score analysis. J Epidemiol Community Health. 2022 Apr;76(4):411-417. doi: 10.1136/jech-2020-216000. Epub 2021 Oct 27. 4. Ansari-Pour N, Zheng Y, Yoshimatsu TF, Sanni A, Ajani M, Reynier J, Tapinos A, Pitt JJ, Dentro S, Woodard A, Rajagopal PS, Fitzgerald D, Gruber AJ, Odetunde, Popoola A, Falusi AG, Babalola CP, Ogundiran T, Ibrahim N, Barretina J, Loo PV, Chen M, White KP, Ojengbede O, Obafunwa J, Huo D, Wedge DC, Olopade OI. Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes. Nature Commun. 2021 Nov 26;12(1):6946. PMID: 34836952 PMCID: PMC8626467 DOI: 10.1038/s41467-021-27079-w 5. Ayandipo OO, Ogun GO, Adepoju OJ, Fatunla EO, Afolabi AO, Osuala PC, Ogundiran TO. Impact of axillary node-positivity and surgical resection margins on survival of women treated for breast cancer in Ibadan, Nigeria. Ecancermedicalscience. 2020;14:1084. doi: 10.3332/ecancer.2020.1084. eCollection 2020. PubMed PMID: 32863878; PubMed Central PMCID: PMC7434507 6. Zheng Y, Walsh T, Gulsuner S, Casadei S, Lee MK, Ogundiran TO, Ademola A, Falusi AG, Adebamowo CA, Oluwasola AO, Adeoye A, Odetunde A, Babalola CP, Ojengbede OA, Odedina S, Anetor I, Wang S, Huo D, Yoshimatsu TF, Zhang J, Felix GES, King MC, Olopade OI. Inherited breast cancer in Nigerian women. J Clin Oncol. 2018 Oct 1; 36(28): 2820–2825. Published online 2018 Aug 21. doi: 10.1200/JCO.2018.78.3977 7. Wang S, Ogundiran TO, Ademola A, Oluwasola OA, Adeoye AO, Sofoluwe A, Morhason-Bello I, Odedina SO, Agwai I, Adebamowo C, Obajimi M, Ojengbede O, Olopade OI, Huo D. Development of a Breast Cancer Risk Prediction Model for Women in Nigeria. Cancer Epidemiol Biomarkers Prev. 2018 Jun; 27(6): 636–643. Published online 2018 Apr 20. doi: 10.1158/1055-9965.EPI-17-1128 8. Wang S, Qian F, Zheng Y, Ogundiran T, Ojengbede O, Zheng W, Blot W, Nathanson KL, Hennis A, Nemesure B, Ambs S, Olopade OI, Huo D. Genetic variants demonstrating flip-flop phenomenon and breast cancer risk prediction among women of African ancestry. Breast Cancer Res Treat. 2018 Apr; 168(3): 703–712. Published online 2018 Jan 4. doi: 10.1007/s10549-017-4638-1 9. Ogundiran TO, Malomo AO, Ezeome ER. Ethics of trauma care. In “Manual of Emergency and Essential Surgical Care in sub-Saharan Africa”. Geneva: WHO; 2017 pp 173- 184. Licence CC BY-NC-SA. 3.0 IGO ISBN 978-929023390-9 10. Ogundiran T. Adebamowo C. Breast Cancer. In “Tropical Hemato-Oncology”. Publisher: Springer. (Editors: Jean-Pierre Droz, Bernard Carme, Pierre Couppié, Mathieu Nacher and Catherine Thiéblemont). 2015 (29):293-302. (ISBN 978-3-319-18256-8; ISBN 978-3-319-18257-5 eBook) DOI 10.1007/978-3-319-18257-5 11. Ogundiran T. Agulanna C. Malomo A. Capacity Building. In “Encyclopedia of Bioethics”. Publisher: Springer Science+Business Media Dordrecht 24 Sep 2015 (Editor: Henk ten Have) pp 1-9. (ISBN 978-3-319-05544-2 Online) DOI 10.1007/978-3-319-05544-2_70-1 12. Sighoko D, Ogundiran T, Ademola A, Adebamowo C, Chen L, Odedina S, Anetor I, Ndom P, Gakwaya A, Ojengbede O, Huo D, Olopade OI. Breast cancer risk after full-term pregnancies among African women from Nigeria, Cameroon, and Uganda. Cancer. 2015 Jul 1;121(13):2237-43. doi: 10.1002/cncr.29305. Epub 2015 Mar 17. Accepted December 23, 2014 13. Ogundiran TO, Ayandipo OO, Adedapo KS, Orunmuyi AT, Ademola AF, Onimode YA, Ayeni OA, Alonge TO. Bone scintigraphy in breast cancer patients in Ibadan, Nigeria. West Afr J Med. 2014 Jul-Sep;33(3):172-7 14. Hou N, Ndom P, Jombwe J, Ogundiran T, Ademola A, Morhason-Bello I, Ojengbede O, Gakwaya A, Huo D. An epidemiologic investigation of physical activity and breast cancer risk in Africa. Cancer Epidemiol Biomarkers Prev. 2014 Dec;23(12):2748-56. doi: 10.1158/1055-9965.EPI-14-0675. Epub 2014 Sep 21. 15. Qian F, Ogundiran T, Hou N, Ndom P, Gakwaya A, Jombwe J, Morhason-Bello I, Adebamowo C, Ademola A, Ojengbede O, Olopade OI, Huo D. Alcohol consumption and breast cancer risk among women in three sub-Saharan African countries. PLoS One. 2014 Sep 8;9(9):e106908. doi: 10.1371/journal.pone.0106908. eCollection 2014 16. Ogundiran TO, Ayandipo OO, Ademola AF, Adebamowo CA. Mastectomy for management of breast cancer in Ibadan, Nigeria. BMC Surg. 2013 Dec 19;13:59. doi: 10.1186/1471-2482-13-59 17. Hou N, Ogundiran T, Ojengbede O, Morhason-Bello I, Zheng Y, Fackenthal J, Adebamowo C, Anetor I, Akinleye S; Olopade OI, Huo D. Risk Factors for pregnancy-associated breast cancer: A report from the Nigerian Breast Cancer Study. Ann Epidemiol. 2013 Sep;23(9):551-7 18. Ogundiran TO, Huo D, Adenipekun A, Campbell O, Oyesegun R, Akang E, Adebamowo C, Olopade OI. Body fat distribution and breast cancer risk: Findings from the Nigerian Breast Cancer Study. Cancer Causes Control. 2012 Apr;23(4):565-74. 19. Ogundiran T, Tuupanen S, Aaltonen LA, Akarolo-Anthony S, Adebamowo C. delGA (rs67491583) variant and colorectal cancer risk in an indigenous African population. Afr. J. Med med. Sci. 2012, 41:271-275 20. Ogundiran TO, Huo D, Adenipekun A, Campbell O, Oyesegun R, Akang E, Adebamowo C, Olopade OI. Case control study of body size and breast cancer risk in Nigerian women. Am JEpidemiol. 2010 Sep 15;172(6):682-90. 21. Ogundiran TO, Adebamowo CA. Surgeons opinions and practice of informed consent in Nigeria. J Med Ethics. 2010 Dec;36(12):741-5. 22. Adebamowo CA, Famooto A, Ogundiran TO, Aniagwu T, Nkwodimmah C, Akang EE. Immunohistochemical and molecular subtypes of breast cancer in Nigeria. Breast Cancer Res Treat. 2008;110(1):183-8 Masters Level 1. Understanding and characteristics of diversity among Nigerian researchers. Abubakar Babangida Usman. Matric No 13798620. Department of Bioethics and Medical Humanities, Faculty of Multidisciplinary Studies, University of Ibadan Fellowship Level 1. Assessment of patients’ satisfaction and early complication rates in patients undergoing day case hernia repair at Connaught Hospital, Freetown, Sierra Leone. Isaac Olufemi Smalle. Department of Surgery, Connaught Hospital, Freetown, Sierra Leone. 2. Effect of fibrin glue on seroma formation after mastectomy and dissection: a randomised control trial. Constantine Ezeme (MBBS, MWACS) Department of Surgery, UCH, Ibadan. West African College of Surgeons. 3. Randomized controlled study using topical tranexamic acid in preventing seroma post mastectomy at University College Hospital, Ibadan. Adegoke Adigun Ishola (MBBS). Department of Surgery, UCH, Ibadan. West African College of Surgeons. 4. Early effects of anthracycline based chemotherapy on left ventricular global longitudinal strain in female breast cancer patients at UCH Ibadan, Nigeria. Dr. Olanike Allison Orimolade (MBBS). Department of Medicine, UCH, Ibadan. Faculty of Internal Medicine, Cardiology Sub-specialty. PREVIOUS STUDENTS Masters Level 1. Expectation, experience and evaluation of participation in a genomics research project in Africa. Raymond Ojo Gbadamosi, Matric No 188545, MSc Bioethics, Department of Surgery, College of Medicine, University of Ibadan. 2017 2. The value of Alvarado score, neutrophil- lymphocyte ratio and C-reactive protein in the diagnosis of acute appendicitis. Ifeanyi Eze. Matric No 189454, MSc Surgery, Department of Surgery, College of Medicine, University of Ibadan. 3. Social, economic, psychological impact and quality of life (SEPIQ) of breast cancer patients at the University College Hospital, Ibadan, Nigeria. Ijeoma Chibuzor, MSc Surgery, Department of Surgery, College of Medicine, University of Ibadan. 2017 4. Knowledge, perception and health-seeking behaviours of women with breast cancer at the University College Hospital, Ibadan, Nigeria. Oluwatosin Esther John. Matric No 116087, MPH, Department of Health Promotion, Faculty of Public Health, College of Medicine, University of Ibadan.2016 5. Comparative analysis of Christian and Muslim women’s views about autonomy in breast cancer genomics research participation in Ibadan, Nigeria. Muhammad Kamaldenn Ahmed. Matric No 173051, MSc Bioethics, Department of Surgery, College of Medicine, University of Ibadan. 2015 6. Ethical challenges in disclosing genomic test results in a developing country. Magbagbeola David Dairo Matric No 47116, MSc Bioethics, Department of Surgery, College of Medicine, University of Ibadan. 2015 7. The role of iodine, selenium and oestrogen in the pathogenesis of breast cancer. Chukwuemelia Zedech Uche Matric No 160391, MSc, Department of ChemicalPathology, College of Medicine, University of Ibadan. 2013 8. The role of peer pressure in research misconduct. Oluwabukola Omowumi Adefemi Matric No 167591, MSc Bioethics, Department of Surgery, College of Medicine, University of Ibadan. 2017 9. Research integrity in selected research institutes in Nigeria. Timothy Shola Abolarinwa Matric No 47224, MSc Bioethics, Department of Surgery, College of Medicine, University of Ibadan. 2014 10. Knowledge and practice of incentives in research participation at Jos University Teaching Hospital. Samuel Odeh Matric No 148570, MSc Bioethics, Department of Surgery, College of Medicine, University of Ibadan 11. Research and medical ethics education among postgraduate students and medical undergraduates in Nigeria. Kayode Omoniyi Osungbade Matric No 30587, MSc Bioethics, Department of Surgery, College of Medicine, University of Ibadan 12. Knowledge of the National Code of Health Research Ethics among biomedical researchers in Nigerian universities and its development for online education. Olubunmi A. Ogunrin Matric No 141478, MSc Bioethics, Department of Surgery, College of Medicine, University of Ibadan 13. Conduct of Ethical research: Perceptions, barriers and motivators in health research community in Nigeria. Adedayo Omokhoa Adeleye Matric No 141477, MSc Bioethics, Department of Surgery, College of Medicine, University of Ibadan 14. Consent for Surgery: a study of information desired by patients in University of Ilorin Teaching Hospital. Raphael O Ayorinde Matric 56907, MSc Surgery, Department of Surgery, College of Medicine, University of Ibadan Doctoral level 1. Effects of radio health programme on women’s attitude to breast cancer screening in Oyo State. Jaiyeola Aramide Oyewole Matric No 58084, Department of Adult Education, Faculty of Education, University of Ibadan 2. Characterization and genetic evolution of breast cancer among Nigerian and Senegalese women. Aniefiok John Udoakang, Universite Cheikh Anta Diop de Dakar, Senegal. 2019 3. Metagenomics and metabolomics of Nigerian women with breast cancer and correlation with diet, nutrition, and mycotoxin exposure. Samson Funminiyi Akinade, Department of Microbiology, Federal University of Agriculture, Abeokuta, Ogun State 4. Breast cancer and spousal relationship in Ibadan metropolis, Oyo state, Nigeria. Morounfoluwa Oluwatosin Oyebola. Department of Sociology, Faculty of the Social Sciences, University of Ibadan Fellowship 1. Effect of intraoperative low dose ketamine infusion in postoperative pain management. David Adedapo Aderinto (MBBS), Department of Anaesthesia, UCH Ibadan. National Postgraduate Medical College of Nigeria 2. Breast ultrasound in evaluation of the response of locally advanced breast cancer to neo-adjuvant chemotherapy at the University College Hospital, Ibadan. Temitope Oluwatosin Soyemi (MBBS), Department of Radiology, UCH, Ibadan. West African College of Surgeons. 2014 3. A comparison of skin staplers and nylon sutures for surgical wound closure in Divisions of General Surgery at UCH, Ibadan, Nigeria. Johnson Bamidele Alegbeleye (BSc, MBBS), Department of Surgery, UCH, Ibadan. National Postgraduate College of Nigeria. November 2016 4. Peri-operative determinants of surgical site infection in general surgery cases. Abdusemmee I. Abdurrazzaaq (MBBS), Department of Surgery, UCH, Ibadan. National Postgraduate College of Nigeria. April 2016 5. Flap fixation versus conventional closure in reducing post-mastectomy seroma. Peter Oluwatobi Elemile (MBBS), Department of Surgery, UCH, Ibadan. West African College of Surgeons. 6. Axillary nodal involvement in breast cancer: correlating clinical examination, axillary ultrasonography and surgical findings with histopathology. Peter Chinyere Osuala, (MBBS, MSc Surgery), Department of Surgery, UCH, Ibadan. West African College of Surgeons. April 2011 7. A comparative study of operative vs non-operative management of uncomplicated acute appendicitis at Connaught Hospital, Freetown, Sierra Leone. Constance Cummings-John. Department of Surgery, Connaught Hospital, Freetown, Sierra Leone. West African College of Surgeons, October 2023. Current 1. Environmental and Genetic Risk Factors for Soft Tissue Sarcomas in Nigeria– A study of the risk factors for soft tissue sarcoma. Funded by the African Research Group for Oncology/Memorial Sloan Kettering Cancer Center, NYC. Role: PI. Collaborators from Federal Medical Centre, Abeokuta and Babcock University, Ilisan 2. Bridging Gaps in the ELSI of Data Science Health Research in Nigeria (BridgELSI). Funded by the NIH, U01 MH127693. Role: MPI (Corresponding PI). Collaborators from the University of Ibadan, Center for Bioethics and Research, University of Maryland, USA, and George Washington University, USA 3. Eastern Nigeria Research Ethics Training (ENRICH) Program, University of Nigeria Teaching Hospital, Enugu. Funded by the NIH R25TW011811 NIH/FIC. Role: MPI. Collaborators from the University of Nigeria, Enugu, Center for Bioethics and Research, and University of Maryland, USA 4. Scaling Up Research Ethics and Research Integrity (SURER) Project. MSc Bioethics training in Responsible Conduct of Research. Funded by the NIH, USA. Role: MPI. Collaborators from the University of Ibadan, Center for Bioethics and Research, Nigeria and University of Maryland, USA. Prof Ogundiran grew up in a traditional African family with farming and blacksmith as the main occupations of his progenitors. In childhood, he took part in farming and blacksmith and also learnt tailoring and playing the accordion. He took part actively in hunting expeditions as he loved running after and killing games the traditional way. His other hobbies include travelling, driving and small scale gardening. Some challenges and hurdles made his early life journey winding and undulating and made him attend primary school, modern school, secondary school, teachers training college, NCE/Polytechnic, and university either partially or fully. However, despite these and other apparent setbacks, he testifies that he has been compensated in diverse ways and through multiple circumstances, too numerous to recount. Prof Ogundiran also grew up in a Baptist family. In his final secondary school year (1975/76), he became a member of the Scriptural Union, a born again Christian group euphemistically called “SU”. He later joined the Maranatha Evangelical Christian Ministry which eventually merged with the Deeper Christian Life Ministry and the Deeper Life Bible Church where he presently serves as a Church Worker. Profile
Designation: Professor
Faculty: CLINICAL SCIENCES
Department: Surgery
Phone Number: +234 8037155946
MBBS (Ibadan), MHSc (Toronto), Cert. Epid & Global Health (Dundee), FWACS, FRCS (Edinburgh), FACS, FAMedSResearch
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