Profile
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Name: Innocent O. IMOSEMI |
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Designation: Reader |
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Faculty: Basic Medical Sciences |
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Department: Anatomy |
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Email: This email address is being protected from spambots. You need JavaScript enabled to view it. Alternate Email Address 1: This email address is being protected from spambots. You need JavaScript enabled to view it. Alternate Email Address 2: This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Biography:
Dr Innocent Ohiorenuan Imosemi graduated with B.Sc. (Hons) degree in Human Anatomy (second class, upper division) from the University of Calabar (1995), obtained a M.Sc. in Anatomy from the University of Ibadan (2001) and a Ph.D. also in Anatomy from the Lagos State University (2011). He received the CONACYT-TWAS postdoctoral fellowship award, 2014 for the advancement of science in developing countries, to pursue a postdoctoral research programme in Mexico. He trained under the supervision of Professor Carolina Escobar at the Department of Anatomy, Faculty of Medicine, National Autonomous University (UNAM) of Mexico from April, 2015-March, 2016. During his postdoctoral training, he learnt the immunohistochemical technique which he used in evaluating the role of Vernonia amygdalina leaf extract in monosodium glutamate-induced oxidative stress in the developing cerebellum of Wistar rats. Dr Imosemi joined the academic staff of the Department of Anatomy, University of Ibadan in 2001 as an Assistant lecturer. He was promoted to lecturer II in 2005, lecturer I in 2008, Senior Lecturer in 2013, Reader in 2018 and has applied for full Professor, 2022. He has been actively involved in teaching, research and community service. He was the coordinator of the B. Pharmacy programme in the Department, 2005-2022, the immediate past Departmental Postgraduate coordinator, April, 2017-February, 2022 and currently the Sub-Dean Postgraduate of the Faculty of Basic Medical Sciences, 2022 to date. He has published over 45 peer-reviewed articles in both local and international journals. He was a member of congregation at Senate, University of Ibadan, 2014-2016 and 2018-2020. Dr Imosemi is a member of the following learned society; Anatomical Society of Nigeria, ASN, Anatomical Society of West Africa, ASWA, Neuroscience Society of Nigeria, NSN, Society of Neuroscientists of Africa, SONA, American Association for Anatomy, AAA and Anatomical Society of the United Kingdom. He is married to Dr Adekunbi F. Imosemi, an Associate Professor of Law, Babcock University, Ilishan-Remo, Ogun State, and the marriage is blessed with children.
Resume
Not Available
Research
Funder: Department research grant
Brief Summary: Aluminium (Al), presents in many manufactured foods and medicines and also added to drinking water for purification purposes has been reported to be neurotoxic in human and animals. Environmental pollution with different aluminium containing compounds, especially those in industrial waste, exposes people to higher-than-normal levels of Al. Although, aluminium has been implicated in Alzheimer's disease, Parkinsonism, Dementia complex and causes extensive damage to the nervous system, to date the mechanism of Al neurotoxicity has not been fully elucidated. Aluminium is a possible contributing factor in Alzheimer’s disease. Evidence for the contribution of Al to Alzheimer’s disease (AD) remains contradictory. However, epidemiological studies have indicated a link between Al in drinking water and AD, and a variety of human and animal studies have implicated learning and memory deficits after Al exposure. Also, aluminium chloride exposure has negative effects on behaviour of adult Wistar rats. Therefore, strategies to attenuate Al-induced impairments could provide a potential protective and therapeutic intervention for its neurotoxicity. The study tends to ascertain if Omega 3 oil possessing high flavonoid and polyphenolic contents will offer protective effects to hippocampus and cerebellum of adult rats exposed to aluminium chloride.
Role: Principal investigator
Collaborators: Testimony Ajibade and Cynthia Tangban
Publications
1. 2004, Malomo, A. O., Imosemi, I. O., Osuagwu, F. C., Oladejo, O. W., Akang, E. E. U. and Shokunbi, M. T. Histomorphometric studies on the effect of cyanide consumption on the developing cerebellum of Wistar rat (Rattus Novegicus) West African Journal of Medicine.
2. 2005, Imosemi, I. O., Malomo, A. O., Oladejo, O. W., Osuagwu, F. C., Ekpo, O. E., Akang, E. E. U. and Shokunbi, M. T. Gross morphometric studies on the effect of cyanide on the developing cerebellum of Wistar rat (Rattus Novegicus). African Journal of Medicine and medical sciences.
3. 2006. Malomo, A. O., Ekpo, O. E., Imosemi, I. O., Owoeye, O., Osuagwu, F. C., Avwioro, O. G. and Shokunbi, M. T. Neuroprotective effect of dexamethasone on the morphology of the irradiated postnatal developing cerebellum of Wistar rats (Rattus Novegicus) International Journal of Morphology.
4. 2010, Imosemi, I. O., Osinubi, A. A. Phenytoin-induced toxicity in the post-natal cerebellar development in rats, Effect of Calotropis procera on histomorphometric parameters International Journal of Morphology.
5. 2012. Imosemi, I. O. The role of antioxidants in cerebellar development. A review of literature. International Journal of Morphology.
6. 2016, Atiba, F. A., Imosemi, I. O. and Malomo A. O. Noxious effect of Moringa oleifera leave extract on the developing brain, morphology and behaviour of Wistar rat International Journal of Anatomy and Embryology.
7. 2016 Imosemi, I. O., Fowosere, O. T. and Atiba, F. A. Honey and vitamin E protected the developing celebellum against alcohol-induced oxidative damage in rats African Journal of Medicine and Medical Sciences.
8. 2016. Imosemi, I. O. and Okori, S. O. Neuroprotective effects of ethanolic leaf extract of Ocimum gratissimum on monosodium glutamate-induced oxidative stress in developing Wistar rat cerebellum African Journal of Medicine and Medical Sciences.
9. 2017 Imosemi, I. O., Adekanmbi, A. J. and Atiba, F. A. Telfairia occidentalis leaf extract protects the cerebellar cortex against cisplatin-induced Oxidative damage in Wistar rat Archives of Basic and Applied Medicine.
10. 2017 Imosemi, I. O., Owolabi, I. S., Owoeye, O. and Malomo, A. O. Protective effect of Carica papaya fruit extract against gamma radiation-induced oxidative damage in postnatal developing rat cerebellum African Journal of Biomedical Research.
11. 2020 Imosemi, I. O. and Owumi, S. E. Diethylnitrosamine induced oxidative stress and morphological changes in the
cerebellum of Wistar rat Archives of Basic and Applied Medicine.
12. 2020 Imosemi, I. O. and Mustapha, W. O. Neuroprotective Potentials of Lycopersicon esculentum fruit extract on Cadmium-induced. toxicity in postnatal developing cerebellum of rats. Anatomy Journal of Africa.
13. 2020. Popoola, A. N. and Imosemi, I. O. Sub-acute evaluation of artesunate, amodiaquine and their combination on muscular coordination and morphology of the cerebellum of Wistar rats International Journal of Biological and Chemical Sciences.
14. 2020 Imosemi, I. O. and Madu, K. M. Protective effects of Camellia sinensis on alcohol-induced oxidative stress in postnatal developing cerebellum of rats. Archives of Basic and Applied Medicine.
15. 2020. Imosemi, I. O., Adu, Y. O., Owoeye, O. and Malomo, A. O. Lead-induced oxidative stress in postnatal developing cerebellum of Wistar rats: role of aqueous extract of Cucumis sativus Linn and vitamin C MOJ Anatomy and Physiology.
16. 2021 Atiba, F. A., Fatokun, A. A., Imosemi, I. O. and Malomo, A. O. Kolanut from Cola nitida Vent. Schott administered to pregnant rats induces histological alterations in pups’ cerebellum. Plos One.
17. 2021. Imosemi, I. O. and Egbo J. U. Aqueous Extracts of Daucus carota (Linn) protected the developing cerebellum of Wistar
rats against perinatal arsenic-induced oxidative Stress Nigerian Journal of Physiological Sciences.
18. 2021. Imosemi, I. O., Owumi, S. E., Arunsi, U. O. Biochemical and histological alterations of doxorubicin-induced neurotoxicity in rats: Protective role of luteolin. Journal of Biochemical and Molecular Toxicology.
19. 2022. Imosemi, I. O. and Oladejo, O. O. Protective effects of Allium Sativum Linn on mercury-induced oxidative stress in the
cerebellum of adult female Wistar rats. African Journal of Biomedical Research Vol. 26. No. 1: 119 – 128.
20. 2023. Okah, L. S., Imosemi, I. O. Carica papaya fruit extract protected the cerebellum of Wistar rats against acrylamide-induced oxidative stress. Nigerian Journal Neuroscience.
Supervision
CURRENT STUDENTS
Masters Level
1. Title: Protective effects of Carica papaya fruit extract against acrylamide-induced oxidative stress in the cerebellum of adult Wistar rats
Student's Name: Okah Leonard Sunday
Examination Body: Postgraduate College
Year: 2018/2019
2. Title: Neuroprotective effects of Omega-3 oil against aluminium chloride-induced oxidative stress on the cerebellum of adult Wistar rats
Student's Name: Tangban Cynthia Nyen
Examination Body: Postgraduate College
Year: 2020/2021
3. Title: Neuroprotective effects of Omega-3 oil against aluminium chloride-induced oxidative stress on the Hippocampus of adult Wistar rats
Student's Name: Ajibade Testimony Priscilla
Examination Body: Postgraduate College
Year: 2020/2021
Doctoral Level
1. Title: Protective effects of Vernonia amygdalina leaf extract on alloxan-induced diabetes and oxidative stress on the hippocampus and cerebellum of adult Wistar rats
Student's Name: Egbo Judith Uzezi
Examination Body: Postgraduate College
Year: 2020/2021
PREVIOUS STUDENTS (Selected)
Masters Level
1. Title: Neuroprotective effects of ethanolic leaf extract of Ocimum gratissimum on monosodium glutamate-induced oxidative stress in developing Wistar rat cerebellum
Student's Name: Okori Stephen O.
Examination Body: Postgraduate College
Year: 2012/2013
2. Title: Protective effects of honey and vitamin E on alcohol- induced oxidative stress in developing Wistar rat cerebellum
Student's Name: Fowosere Owobusola T.
Examination Body: Postgraduate College
Year: 2012/2013
3. Title: Protective effects of Daucus carota Linn on arsenic-induced oxidative stress in postnatal developing cerebellum of Wistar rats
Student's Name: Egbo Judith Uzezi
Examination Body: Postgraduate College
Year: 2016/2017
4. Title: Protective effects of Lycopersicon esculentum fruit extract on cadmium-induced oxidative stress in postnatal developing cerebellum of Wistar rats
Student's Name: Mustapha, Olufunke Wuraola
Examination Body: Postgraduate College
Year: 2016/2017
5. Title: Protective effects of Camellia senensis on alcohol-induced oxidative stress in postnatal developing cerebellum of Wistar rats
Student's Name: Madu Kelechi Maxwell
Examination Body: Postgraduate College
Year: 2016/2017
6. Title: Protective effects of Allum sativum Linn (Garlic) on mercury-induced oxidative stress in cerebellum of adult Wistar rats
Student's Name: Oladejo Olalekan Olumide
Examination Body: Postgraduate College
Year: 2016/2017
Doctoral level
1. Title: Neurobehavioural and histomorphological changes in the hippocampus and cerebellum of Wistar rats treated with artesunate and amodiaquine
Student's Name: Popoola AbdulGafar Niyi
Examination Body: Postgraduate College
Year: 2020/2021
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