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Name: Imran O. MORHASON-BELLO
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| Designation: Professor |
| Faculty: Clinical Sciences |
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Department: Obstetrics and Gynaecology
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| Phone Number: +234 8034784402 |
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Google Scholar Profile
Research Gate Profile
ORCID Profile |
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Biography:
Professor. Imran O. Morhason-Bello, an indigene of Ayetoro-Oke (Kajola LGA, Oyo State) is an alumnus of University of Ibadan, University of Liverpool, and London School of Hygiene and Tropical Medicine London, UK. He did his residency training programme at the University College Hospital, Ibadan to obtain a Fellowship of West African College of Surgeon and National Postgraduate Medical College in the Faculty of Obstetrics and Gynaecology. He currently holds a joint appointment with University of Ibadan and University College Hospital, Ibadan in the Department of Obstetrics and Gynaecology. He is a Professor and Honourary Consultant. He is also a Clinical Epidemiologist and certified trainer in Management and Leadership.
Professor Morhason-Bello’s clinical and research portfolio covers different aspects of Women Health with special interest in Genito-urinary Medicine/Urogynaecology (Female Pelvic Medicine and Reconstructive Surgery), Gynae-oncology, Infectious Diseases, Sexual and Population Health. He is currently leading several funded research grants on human papillomavirus related conditions in different anatomic sites including cervix, anal, oral and oro-pharyngeal precancer and cancers with multidisciplinary team at the College of Medicine, University of Ibadan, Ibadan and other institutions in USA and United Kingdom. Some of these projects include BigCAT by AACR, R01, U01 and Catalyzer grants funded by AACR, NIH and Northwestern University, USA amongst others. He led Sexual Behavior and HPV infections in Nigerians in Ibadan (SHINI) study - one of the largest population epidemiological studies in Sub-Saharan Africa on multiple anatomic sites HPV infections and morbidities (cervical, anal, vulvar penile and oral cavity) with over 10,000 duplicate biological samples among brothel-based female sex workers, women, and men in the general population in Nigeria.
He is a dedicated lecturer with extensive experience in teaching, mentoring, and examining medical students, resident doctors, and postgraduates. He has supervised numerous dissertations and theses for resident doctors, as well as master’s and PhD students at both the University of Ibadan and the Pan African University Life and Earth Sciences Institute.
He consults for several international organizations on women’s health including emergency obstetric care and sexual and reproductive health training manual and development of protocols and guidelines on different aspects of Women health in Nigeria. He is a member to many international organizations and serving on many technical working committees on Women Health. He served on the Board of Medical and Dental Council of Nigeria (MDCN), and MDCN Disciplinary Tribunal Panel (2018-2022). He is also on the board of some corporate organizations.
Professor Morhason-Bello has over 250 publications in peer reviewed scientific journals, monographs, and chapters of scientific books. He has won several prizes and awards in recognition of his performance at different stages of his education and career.
He is happily married with children.
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Current Research
- Title: Epigenetic Biomarkers of Anal HPV Infection in Women with Cervical HPV (BIG CAT)
Funder: American Association for Cancer Research (AACR)
Brief Summary : There is emerging evidence that HPV-associated anal precancer and cancer are increasingly being reported, particularly among women with history of high-risk HPV (hrHPV) infections, premalignant or cancer of the cervix who had no history of anal sex. However, there is no scientific evidence to justify advocating screening for anal hrHPV infections in women presenting for cervical HPV screening in future, particularly in countries like Nigeria where there is limited access and infrastructure to support multiple visits and screening for cancers in women. The research plan is to evaluate epigenetic biomarkers to explain biological insights on the mechanism of HPV infection and identify the HPV-infected people who are at risk of progression to invasive cervical and anal cancers by conducting a secondary laboratory analysis of biological samples collected and stored from the Sexual Behaviors and HPV infections in Nigerians in Ibadan (SHINI) study. We hypothesize that the DNA methylation (DNAm) in the blood and/or anal swab could predict the susceptibility of women with no history of anal sex to acquire hrHPV in the anus, of those that have hrHPV in the cervix.
Role: Principal Investigator
Collaborators: Northwestern University, USA
- Title: Epigenetics of Oral HPV and associated Oral/Oropharyngeal Cancer in people living with HIV in Nigeria (EpOOCH study)
Funder: R01 National Cancer Institute (NCI)/National Institutes of Health (NIH) Grant
Brief Summary : This project focuses on identifying epigenetic markers specific to HIV-associated OOPC by comparing non-HPV-infected OOPC cases and HIV-infected cancer-free PLWH in one of the most populous nations with prevalent HIV. Most prior studies on epigenetic markers of OOPC included few HPV-infected cases with HIV, leaving a large and problematic gap in our current understanding of how these infections interact to promote OOPC in the population that is most severely affected by it, and the epigenomic mechanisms that might be involved. Understanding the role of DNAm in HPV-associated OOPC will help develop targeted interventions to improve prevention and early detection of OOPC among PLWH. While the problem of HPV–associated OOPC in PLWH is largely due to poor screening methods and availability, understanding the underlying epigenetic markers in premalignant lesions of OOPC that are predictive of progression to invasive cancer could potentially lead to more targeted triage early detection and treatment of the subpopulation of men and women with both OOPC and markers associated with progression, resulting in substantial and cost-effective improvement in outcomes critical for health interventions to succeed not only in resource-limited countries such as Nigeria but also others around the world.
Role: Principal Investigator
Collaborators: Northwestern University, Chicago, IL. And Satellite Recruitment Sites in 12 Teaching Hospitals/Federal Medical Centers in Nigeria
- Title: West Africa Self-Sampling HPV Based Cervical Cancer Control Program (WASSH-CC)
Funder: National Cancer Institute (NCI) of the United States
Brief Summary: HPV, a major cause of CC, is the most common sexually transmitted infection in SSA and nearly all WLWHA worldwide who develop CC are co-infected with HPV. CC is largely preventable by HPV vaccination and cervical screening for early detection and treatment. In high income countries (HICs), these strategies have led to a steep decline in CC; however, they remain largely inaccessible to women in low- and middle-income countries (LMICs). Self-sampling-based HPV (SS-HPV) tests have been shown to be a cost-effective and feasible approach to identifying women infected with high-risk HPV strains (hr-HPV) who need more advanced diagnostic tests and treatment. However, SS-HPV testing has not been widely implemented in most LMICs, including SSA despite high HIV prevalence. Leveraging our decade-long, extensive, and successful training partnership and research collaborations in Mali and Nigeria, we are currently conducting an implementation science project entitled West African Self-Sampling HPV-Based Cervical Cancer Control Program (WASSH-CC). The project is operationalizing SS-HPV testing within the Nigerian HIV program.
Role: Site Principal Investigator
Collaborators: Northwestern University, USA, University of Sciences, Techniques and Technologies of Bamako (USTTB) Mali, Jos University, Jos, Nigeria.
- Title: Epigenetic Biomarkers of Cervical Cancer in Women with HPV Infection in Multiple Sites (Catalyzer grants)
Funder: Institute for Global Health, Northwestern University, Chicago, IL
Brief Summary: Studies have shown that HPV-positive cervical, anal, and oral cancers have elevated levels of DNA methylation compared to normal tissues, indicating that DNA methylation can play a role in the persistence of HPV infection and the development of HPV-related cancers in these sites. In addition, there is evidence to suggest that DNA methylation can be influenced by environmental and lifestyle factors, such as tobacco smoke and alcohol consumption, which can impact the risk of HPV infection and the persistence of the virus in multiple sites. Therefore, understanding the role of DNA methylation in HPV infection in multiple sites may provide us with more insights into persistent cervical cancer HPV infection and cervical cancer development.
Role: Principal Investigator
Collaborators: Northwestern University, USA
- Title: R01 National Cancer Institute (NCI)/National Institutes of Health (NIH) Supplement Grant
Funder: R01 National Cancer Institute (NCI)/National Institutes of Health (NIH) Grant
Brief Summary : Oral and oropharyngeal cancers (OOPCs) are increasingly being reported in many countries, with higher proportions being associated with human papillomavirus (HPV) infection. Globally 29,000 new HPV-associated OOPC cases are every year. The OOPC-related death rate is relatively high compared to other HPV-associated cancers (HACs), mainly due to late presentation or detection in nearly 55-60% at an advanced stage. Most (>70%) of cases and deaths from OOPCs worldwide occur in LMICs, mostly in Asia and Africa. Currently, there is a lack of universal screening strategy for women with oral or oropharyngeal cancer compared to cervical cancer. This project leverages our ongoing NIH/NCI-funded R01 study by investigating the importance of epigenetic biomarkers as a potential screening tool to predict the susceptibility and risk of having hrHPV in the cervix of women living with HIV who either have a hrHPV or HPV-associated precancer cancer in the oral and oropharyngeal sites. This project is primarily designed to mentor an Early-Stage Low and middle-Income countries Investigator (ELSI).
Role: LMIC Co-mentor
Collaborators: Northwestern University, Chicago, IL
Selected Publications
Books
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Year of Publication
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Authors/Editors
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Title
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Publisher
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1
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2017
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Adewole, I.F., Dennis, L., Odedina, F., Rebbeck, A. and Morhason- Bello, I.O.
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Cancer Plan for the African Continent (2013-2017)
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Royal Bird Ventures
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2
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2022
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Adewole IF, Oluwasola TA, Morhason-Bello IO
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Building Capacity to Control Cervical Cancer in Nigeria: a Case Study. In Approaching Global Oncology: The win-win model
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IOP Publishing
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3
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2017
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Morhason- Bello, I.O. and Oladokun, A/ E. Oluwabunmi Olapade-Olaopa, J Kayode Ladipo, Adesina Oladokun Simbo D Amanor- Boadu (ED)
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Postpartum Haemorrhage. Manual of Emergency and Essential Surgical Care in Sub-Saharan Africa
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Wadell
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4
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2016
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Adesina, O.A. and Morhason- Bello, I.O./ Edward Ejiro Emuveyan, Akinyinka Omigbodun, Bissallah Ahmed Ekele, Mike Kamara, Joseph Darkwa Seffah (ED)
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Cardiovascular Changes in Pregnancy. Basic Science of Obstetrics and Gynaecology for Postgraduates.
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Wadell
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Journal Articles
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Year of Publication
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Authors/Editors
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Title
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Publisher
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1
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2024
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Rume J, Morhason-Bello IO, Oladokun A.
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Perception, interpretation, and implication of non-penile vaginal sex among young adults in tertiary institutions in Northcentral Nigeria.
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African Journal of Reproductive Health
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2
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2024
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Vogel JP, Jung J, Lavin T, Simpson G, Kluwgant D, Abalos E, Diaz V, Downe S, Filippi V, Gallos I, Galadanci H, Katageri G, Homer CSE, Hofmeyr GJ, Liabsuetrakul T, Morhason-Bello IO, Osoti A, Souza JP, Thakar R, Thangaratinam S, Oladapo OT
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Neglected medium-term and long-term consequences of labour and childbirth: a systematic analysis of the burden, recommended practices, and a way forward.
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The Lancet Global Health
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3
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2023
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Morhason-Bello IO, Mitchell K, Jegede AS, Adewole IF, Francis SC, Watson-Jones D.
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Heterosexual Oral and Anal Sex: Perceptions, Terminologies, and Attitudes of Younger and Older Adults in Ibadan, Nigeria.
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Archives of Sexual Behaviour
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4
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2023
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Yang L, Boily MC, Rönn MM, Obiri-Yeboah D, Morhason-Bello I, Meda N, Lompo O, Mayaud P, Pickles M, Brisson M, Hodgins C.
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Regional and country-level trends in cervical cancer screening coverage in sub-Saharan Africa: A systematic analysis of population-based surveys (2000–2020).
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The Public Library of Science (PLoS one)
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5
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2023
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Dinga JN, Kabakama S, Njimoh DL, Chia JE, Morhason-Bello I, Lumu I.
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Quantitative Synthesis of Factors Associated with COVID-19 Vaccine Acceptance and Vaccine Hesitancy in 185 Countries. Vaccines.
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Multidisciplinary Digital Publishing Institute (MDPI)
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6
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2022
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Morhason-Bello IO, Baisley K, Pavon MA, Adewole IF, Bakare RA, de Sanjosé S, Francis SC, Watson-Jones D.
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Oral, genital and anal human papillomavirus infections among female sex workers in Ibadan, Nigeria.
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The Public Library of Science (PLoS one)
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7
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2022
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Wei F, Xia N, Ocampo R, Goodman MT, Hessol NA, Grinsztejn B, Ortiz AP, Zhao F, Kojic EM, Kaul R, Heard I, Morhason Bello IO, Moscicki AB, de Pokomandy A, Palefsky JM, Rodrigues LLS, Mandishora RSD, Ramautarsing RA, Franceschi S, Godbole SV, Tso FK, Menezes LJ, Lin C, Clifford GM.
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Age-specific prevalence of anal and cervical HPV infection and high-grade lesions in 11 177 women by HIV status: a collaborative pooled analysis of 26 studies.
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Journal of Infectious Diseases
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8
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2022
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Morhason-Bello IO, Adebamowo CA
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Epidemiology of uterine fibroid in black African women: a systematic scoping review.
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BMJ Open
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9
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2021
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Morhason-Bello IO, Baisley K, Pavon MA, Adewole IF, Bakare R, de Sanjosé S, Francis SC, Watson-Jones D
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Prevalence and genotype specific concordance of oro-genital and anal human papillomavirus infections among sexually active Nigerian women. Infect Agent Cancer.
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Infectious Disease and Cancer
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10
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2020
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Morhason-Bello IO, Kareem YO, Adewole IF
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Modeling for Predictors of Knowledge Score on Etiology and Prevention Strategies for Cervical Cancer Among Women of Reproductive Age in Ibadan.
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JCO Global Oncology
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11
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2020
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Morhason-Bello IO, Fagbamigbe AF, Kareem YO, Ojengbede OA.
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Economic status, a salient motivator for medicalisation of FGM in sub-Saharan Africa: Myth or reality from 13 national demographic health surveys.
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SSM- Population Health
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12
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2019
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Morhason-Bello IO, Kabakama S, Baisley K, Francis SC, Watson-Jones D
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Reported oral and anal sex among adolescents and adults reporting heterosexual sex in sub-Saharan Africa: a systematic review.
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Reproductive Health
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13
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2019
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Bello OO, Morhason-Bello IO, Lawal OO, Abdussalam RA, Ojengbede OA.
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Knowledge of front-line health workers on the role of urethral catheterization for primary prevention of obstetric fistula in Ibadan, Nigeria.
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Translational Andrology and Urology
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14
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2018
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Morhason-Bello IO, Kareem YO, Abdus-Salam RA, Bello OO, Lawal OO, Akinlusi FM, Abegunde LO, Ojengbede O
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Factors associated with the awareness of vaginal fistula among women of reproductive age: findings from the 2018 Nigerian demographic health cross-sectional survey.
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BMJ Open
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15
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2016
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Miller S, Abalos E, Chamillard M, Ciapponi A, Colaci D, Comandé D, Diaz V, Geller S, Hanson C, Langer A, Manuelli V, Millar K, Morhason-Bello I, Castro CP, Pileggi VN, Robinson N, Skaer M, Souza JP, Vogel JP, Althabe F
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Beyond too little, too late and too much, too soon: a pathway towards evidence-based, respectful maternity care worldwide.
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The Lancet Global Health
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16
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2013
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Ojengbede OA, Morhason-Bello IO.
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Vesico-vaginal fistula repair as a day case: is it a worthy venture?
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International Urogynecol Journal
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17
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2012
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Morhason-Bello IO, Ojengbede OA, Adedokun BO, Okonkwo NS, Kolade C
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Theories of urinary incontinence causation: aetiological descriptions by sub-Saharan African women.
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European Journal of Obstetrics & Gynaecology and Reproductive Biology
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18
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2011
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Ojengbede OA, Morhason-Bello IO, Adedokun BO, Okonkwo NS, Kolade CO.
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Prevalence and the associated trigger factors of urinary incontinence among 5000 black women in sub-Saharan Africa: findings from a community survey.
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British Journal of Urology International
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19
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2009
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Morhason-Bello IO, Adedokun BO, Ojengbede OA, Olayemi O, Oladokun A, Fabamwo AO.
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Assessment of the effect of psychosocial support during childbirth in Ibadan, south-west Nigeria: a randomised controlled trial.
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Australian and New Zealand Journal of Obstetrics and Gynaecology
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20
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2007
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Oladokun A, Morhason-Bello, IO, Enakpene CA, Akinyemi O, Owonikoko KM, Obisesan KA
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Sexual behaviour and contraceptive usage of secondary school adolescents in Ibadan, Nigeria
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Journal of Reproduction and Contraception
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CURRENT STUDENTS
Master’s Level:
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S/N
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Title
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Student’s Name
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Year of Entry
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1.
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Perception/Interpretation and Attitude of First-Time Mothers towards Caesarean Section (A Mixed Method Study)
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Olalude Olajumoke Ayisat
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2022
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Doctoral Level:
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S/N
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Title
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Student’s Name
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Year of Entry
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1
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Evaluation of the Role of Common Salt and Msg Intake in the Pathophysiology of Testosterone-Induced Benign Prostatic Hyperplasia in Adult Male Wistar Rats (Pan African University Program, University of Ibadan)
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Idris Bello
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2020
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2
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Non-Penile Vaginal Sexual Behaviour and Associated Health Risks among Young Adults in Tertiary Institutions in the Central Senatorial District of Plateau State Nigeria (Pan African University Program, University of Ibadan)
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Juliana Rume
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2021
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3
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Preference, attitude, and concerns of women on self-sampling versus healthcare providers’ sampling for Human papillomavirus test for cervical cancer screening in Ibadan (Pan African University Program, University of Ibadan)
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Andrew Bassey Uduak
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2022
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4
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Ensemble machine learning models of Human papillomavirus infections in Ibadan, Southwestern Nigeria (Epidemiology and Medical Statistics, University of Ibadan)
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Oke Olamiposi
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2021
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5.
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Effect of Mobile Health (mHealth) interventions for cervical cancer screening among reproductive age women in Osun State Nigeria
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Lolade C. Oyedero
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2023
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Fellowship Level:
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S/N
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Title
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Student’s Name
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Year of Entry
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1
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Assessment of Lower Urinary Tract Symptoms in Postpartum Women with or without Genital Tract Laceration after Vagina Delivery in University College Hospital, Ibadan
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Dr. J. Ogunsola
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2023
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2
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Incidence and Risk Factors for Female Sexual Dysfunction in Pregnancy and Postpartum Period at University College Hospital, Ibadan
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Dr. O. Adedeji
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2023
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3
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Prevalence of and Associated Factors for Human papilloma Infections among Pregnant Women and their Newborns at University College Hospital, Ibadan
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Dr. A.T Sanusi
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2023
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4
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A Randomized Control Trial of the Association between Antenatal Pelvic Exercise and Risk of Genital Trauma and Childbirth Outcomes in Nullipara Women
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Dr. T.A Olukunle
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2023
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5
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Vaginal Fluid, Urea and Creatinine in the Diagnosis of Prelabour Rupture of Membrane
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Dr. O. Ojediran
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2023
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6
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Postpartum Voiding Dysfunction Following Elective Caesarean Section at University College Hospital, Ibadan
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Dr. E. Salufu
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2023
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7
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Adjunctive Use of Intravenous Tranexamic Acid with Catheter on Blood Loss on Abdominal Myomectomy
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Dr. B.A. Esan
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2023
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8
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Prevalence and Risk Factors of Anal Incontinence among Women after Childbirth at the University College Hospital, Ibadan
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Dr. Linda Audu
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2023
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9
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Comparison of Cervicovaginal High Risk Human papillomavirus among Women with and without Pelvic Organ Prolapse in Ibadan
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Dr. A. F. Ameh
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2023
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PREVIOUS STUDENTS (Selected)
Master’s Level:
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S/N
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Title
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Student’s Name
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Year of Entry
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1.
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Determinants of Compliance with Routine Antenatal Haematinics among Pregnant Women in Kpalime (Kloto District), Togo (Pan African University Program, University of Ibadan)
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Dogbe Dede Melissa
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2020
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2
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Perception, Attitude and Factors Influencing the Intention to Utilize Cervical Cancer Prevention Strategies among Pregnant Women in Ibadan (Pan African University Program, University of Ibadan)
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Ani Odinaka Benardette
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2021
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Fellowship:
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S/N
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Title
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Student’s Name
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Year of Entry
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1.
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Association between Vaginal Birth and Postpartum Urinary Retention in Women Delivered in a Tertiary Health Facility in Nigeria.
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Dr. Olatunji Lawal
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2015
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2.
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The Effect of Pre-eclampsia on Ocular changes in Pregnancy: A Case Control Study at the University College Hospital, Ibadan.
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Dr. Chimelie Onwudiegwu
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2016
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3.
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Estimation of Selected Inflammatory Cytokines in Maternal Serum for Assessing the Outcome of Threatened Miscarriage in Ibadan
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Dr. AbdulHakeem Adewale Lawal
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2021
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Playing golf, watching football, walking long distances.
